502925-44-2Relevant articles and documents
Aminopyrimidine Kinase Inhibitors
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Page/Page column 78, (2012/11/07)
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFβ pathway, the Wnt pathway, the J
Biomimetic aryl hydroxylation derived from alkyl hydroperoxide at a nonheme iron center. Evidence for an FeIV=O oxidant
Jensen, Michael P.,Lange, Steven J.,Mehn, Mark P.,Que, Emily L.,Que Jr., Lawrence
, p. 2113 - 2128 (2007/10/03)
Many nonheme iron-dependent enzymes activate dioxygen to catalyze hydroxylations of arene substrates. Key features of this chemistry have been developed from complexes of a family of tetradentate tripodal ligands obtained by modification of tris(2-pyridyl