503184-29-0Relevant articles and documents
CRF ligands via Suzuki and Negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine.
Arvanitis, Argyrios G,Arnold, Charles R,Fitzgerald, Lawrence W,Frietze, William E,Olson, Richard E,Gilligan, Paul J,Robertson, David W
, p. 289 - 291 (2003)
A series of imidazo[4,5-b]pyridines with a 7-(3-pyridyl) substituent is described as high affinity CRF receptor ligands. Individual analogues were synthesized from key intermediates obtained via palladium-catalyzed coupling of 3-pyridyl zinc or boronic acid organometallic intermediates with 2-benzyloxy-4-chloro-3-nitropyridine 12.
