503417-37-6

Basic information

• Product Name: Cyclopropanamine, 1-(2-pyridinyl)- (9CI)
• Synonyms: Cyclopropanamine, 1-(2-pyridinyl)- (9CI);1-(Pyridin-2-yl)cyclopropanamine;1-(2-Pyridyl)cyclopropylaMine;1-(pyridin-2-yl)cyclopropan-1-aMine;1-(2-pyridinyl)-CyclopropanaMine;2-(1-Aminocyclopropyl)pyridine;1-(PYRIDIN-2-YL)CYCLOPROPANAMINE 2HCL;Cyclopropanamine, 1-(2-pyridinyl)-
• CAS NO: 503417-37-6
• Molecular Formula: C₈H₁₀N₂
• Molecular Weight: 134.1784
• Product Categories: PYRIDINE
• Mol File: 503417-37-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 62℃
• Boiling Point: 239℃
• Flash Point: 121℃
• Appearance: /
• Density: 1.150
• Vapor Pressure: 0.042mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: 2-8°C
• PKA: 7.82±0.20(Predicted)
• CAS DataBase Reference: Cyclopropanamine, 1-(2-pyridinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanamine, 1-(2-pyridinyl)- (9CI)(503417-37-6)
• EPA Substance Registry System: Cyclopropanamine, 1-(2-pyridinyl)- (9CI)(503417-37-6)

Safety Data

• Hazardous Substances Data: 503417-37-6(Hazardous Substances Data)

Usage

General Description

Cyclopropanamine, 1-(2-pyridinyl)- (9CI) is a specific chemical substance which holds a distinct structural formula. The nomenclature falls under the 9th Collective Index (9CI) which categorizes it in terms of its chemical functionality and structural features. The compound features a cyclopropane ring which is a form of amine that contains a three-membered ring of carbon atoms. In this specific compound, one of these compounds is substituted with a 2-pyridinyl group, which serves as an aromatic heterocyclic compound similar to benzene and pyridine, thus defining its structural uniqueness and probable chemical behavior which would be highly pertinent in various chemical reactions or applications. Further details such as its exact molecular weight, physical and chemical properties, toxicity, or relevant applications would be found in more exhaustive databases or material safety data sheets.

InChI:InChI=1/C8H10N2/c9-8(4-5-8)7-3-1-2-6-10-7/h1-3,6H,4-5,9H2

Upstream product

• 100-70-9 2-Cyanopyridine 
• 925-90-6 ethylmagnesium bromide 
• 557-20-0 diethylzinc 
• 162960-26-1 1-(pyridin-2-yl)cyclopropanecarboxylic acid 
• 1658-42-0 methyl 2-pyridylacetate 
• 162960-27-2 methyl 1-(pyridin-2-yl)cyclopropanecarboxylate 

Downstream Products

• 873221-80-8 (1-pyridin-2-ylcyclopropyl)carbamic acid tert-butyl ester 
• 1056459-44-9 4-[5-(3,5-Dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazole-3-yl]-2-methyl-N-[1-(2-pyridyl) cyclopropyl] benzamide 
• 1215107-12-2 3-iodo-N-(1-(pyridin-2-yl)cyclopropyl)benzamide 
• 1215107-10-0 3-iodo-4-methyl-N-(1-(pyridin-2-yl)cyclopropyl)benzamide 
• 1240521-74-7 (S)-N-(2-methoxy-5-(pyridin-4-yl)pyridin-3-yl)-3-phenyl-2-(1-(pyridin-2-yl)cyclopropylamino)propanamide 
• 1215105-53-5 6-(N-ethylmethylsulfonamido)-2-(4-fluorophenyl)-N-methyl-5-(3-(1-(pyridin-2-yl)cyclopropylcarbamoyl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide 
• 1215107-13-3 N-(1-(pyridin-2-yl)cyclopropyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 
• 1239013-76-3 2-(4-((1-(pyridin-2-yl)cyclopropyl)amino)phenyl)benzo[d][1,3,2]dithiazole 1,1,3,3-tetraoxide 
• 1341167-87-0 N-(1-(pyridin-2-yl)cyclopropyl)benzene-1,4-diamine 

Relevant articles and documents

Process development and pilot-plant synthesis of (S)-tert-butyl 1-oxo-1-(1-(pyridin-2-yl)cyclopropylamino)propan-2-ylcarbamate: Studies on the scale-up of Kulinkovich-Szymoniak cyclopropanation

A practical and scalable synthesis of (S)-tert-butyl 1-oxo-1-(1-(pyridin-2- yl)cyclopropylamino)propan-2-ylcarbamate, an intermediate in the manufacture of a lymphocyte function-associated antigen 1 inhibitor, is described. The titled compound is prepared via an efficient one-pot, two-step telescoped sequence starting from readily available materials. A modified Kulinkovich-Szymoniak cyclopropanation of a nitrile followed by in situ amide formation with an activated carboxylic acid derivative afforded the target product in about 50% overall isolated yield and >97% purity.

PIPERAZINE AND HOMOPIPERAZINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS

Compounds of Formula I, including pharmaceutically acceptable salts thereof, are useful as HIV attachment inhibitors.

ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS

Use of substituted sulfonamides of the formula (I) or salts thereof for enhancing stress tolerance in plants to abiotic stress, especially for enhancing plant growth and/or for increasing plant yield.