503424-79-1 Usage
Description
(3-Methyl-1-benzothien-5-yl)acetonitrile, also known as 3-methylbenzothiophene-5-acetonitrile, is a benzothiophene derivative featuring a methyl group at the third position and a cyano group at the fifth position. This chemical compound is recognized for its versatile reactivity and functionalization potential, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
(3-Methyl-1-benzothien-5-yl)acetonitrile is used as a key intermediate in the synthesis of various drugs. Its unique structure and chemical properties contribute to the development of new medicinal compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, (3-Methyl-1-benzothien-5-yl)acetonitrile serves as a crucial component in the creation of pesticides. Its reactivity and functionalization potential allow for the design of effective and targeted agrochemical products.
Used in Organic Reactions and Mechanisms Study:
(3-Methyl-1-benzothien-5-yl)acetonitrile is also utilized in the study of organic reactions and mechanisms. Its distinct chemical properties provide researchers with valuable insights into the behavior of similar compounds and contribute to the advancement of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 503424-79-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,4,2 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 503424-79:
(8*5)+(7*0)+(6*3)+(5*4)+(4*2)+(3*4)+(2*7)+(1*9)=121
121 % 10 = 1
So 503424-79-1 is a valid CAS Registry Number.
503424-79-1Relevant articles and documents
Assembly of α-(Hetero)aryl Nitriles via Copper-Catalyzed Coupling Reactions with (Hetero)aryl Chlorides and Bromides
Chen, Ying,Xu, Lanting,Jiang, Yongwen,Ma, Dawei
, p. 7082 - 7086 (2021)
α-(Hetero)aryl nitriles are important structural motifs for pharmaceutical design. The known methods for direct synthesis of these compounds via coupling with (hetero)aryl halides suffer from narrow reaction scope. Herein, we report that the combination of copper salts and oxalic diamides enables the coupling of a variety of (hetero)aryl halides (Cl, Br) and ethyl cyanoacetate under mild conditions, affording α-(hetero)arylacetonitriles via one-pot decarboxylation. Additionally, the CuBr/oxalic diamide catalyzed coupling of (hetero)aryl bromides with α-alkyl-substituted ethyl cyanoacetates proceeds smoothly at 60 °C, leading to the formation of α-alkyl (hetero)arylacetonitriles after decarboxylation. The method features a general substrate scope and is compatible with various functionalities and heteroaryls.
