503544-95-4

Basic information

• Product Name: 4-Pyridinecarboxaldehyde, 1,2,3,6-tetrahydro-1-(phenylmethyl)-
• CAS NO: 503544-95-4
• Molecular Formula: C13H15NO
• Molecular Weight: 201.268
• Mol File: 503544-95-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Pyridinecarboxaldehyde, 1,2,3,6-tetrahydro-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxaldehyde, 1,2,3,6-tetrahydro-1-(phenylmethyl)-(503544-95-4)
• EPA Substance Registry System: 4-Pyridinecarboxaldehyde, 1,2,3,6-tetrahydro-1-(phenylmethyl)-(503544-95-4)

Safety Data

• Hazardous Substances Data: 503544-95-4(Hazardous Substances Data)

Upstream product

• 503545-00-4 1-benzyl-2,6-dioxo-1,2,3,6-tetrahydropyridine-4-carboxylic acid ethyl ester 
• 330173-08-5 N-benzyl-2-(4-methylphenylsulfonyl)acetamide 
• 158984-76-0 1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinemethanol 

Downstream Products

• 68547-97-7 Isoguvacine hydrochloride 
• 22065-85-6 N-benzyl-4-formylpiperidine 
• 79858-48-3 1-benzyl-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid 

Relevant articles and documents

New approach to N-substituted-1,2,3,6-tetrahydro-pyridine-4-carbaldehyde, a precursor for synthesizing Aricept, isoguvacine, and deethylibophyllidine

A new route towards the synthesis of N-substituted-4-formylpiperidine using N-benzyl or tryptaminylsulfonylacetamide and α,β-unsaturated ester as starting materials is described. Formal synthesis of Aricept, deethylibophyllidine, and isoguvacine, which have potential biological activities, were synthesized via this strategy.

An efficient synthesis of N-alkyl-4-substituted 3H-pyridine-2,6-dione. Synthesis of isoguvacine and MDL-11,939

An efficient route towards the synthesis of N-alkyl-4-substituted 3H-pyridine-2,6-dione using various N-alkyl-α-sulfonylacetamides and two α,β-unsaturated esters as starting materials is described. Isoguvacine and MDL-11,939 with have potential biological activities were synthesized via this strategy.