503615-07-4

Basic information

• Product Name: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
• Synonyms: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate;6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester;1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 6-(4-aMinophenyl)-4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-, ethyl ester;Apixaban interMediate;ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
• CAS NO: 503615-07-4
• Molecular Formula: C22H22N4O4
• Molecular Weight: 406.43448
• EINECS: 1312995-182-4
• Mol File: 503615-07-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 651.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility: Chloroform (Slightly), DMF (Slightly)
• PKA: 4.66±0.10(Predicted)
• CAS DataBase Reference: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate(503615-07-4)
• EPA Substance Registry System: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate(503615-07-4)

Safety Data

• Hazardous Substances Data: 503615-07-4(Hazardous Substances Data)

Usage

Description

Ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is a chemical compound that is identified as an impurity in Apixaban (A726700), a potent and selective inhibitor of coagulation factor Xa. ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate plays a significant role in the pharmaceutical industry due to its association with a drug that has various therapeutic applications.

Uses

Used in Pharmaceutical Industry:
Ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is used as an impurity in the production of Apixaban, a drug with potential applications in the prevention of venous thromboembolism in orthopedic surgeries such as total hip and knee replacement. It is also useful in the treatment of patients with venous thromboembolic disorder or atrial fibrillation, as it helps in the management and prevention of stroke.
Additionally, due to its association with Apixaban, this compound may be relevant in research and development for new oral coagulants, further expanding its applications in the pharmaceutical industry.

Physical Form

Solid