50375-72-9

Basic information

• Product Name: Phosphonic acid, [(2-hydroxyphenyl)methyl]-, diethyl ester
• Synonyms: diethyl 2-hydroxybenzylphosphonate;diethyl hydroxybenzylphosphonate;2-DIETHYLPHOSPHONOMETHYL PHENOL
• CAS NO: 50375-72-9
• Molecular Formula: C11H17O4P
• Molecular Weight: 244.227
• Mol File: 50375-72-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 120 °C(Press: 1.5 Torr)
• Density: 1.179±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Phosphonic acid, [(2-hydroxyphenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(2-hydroxyphenyl)methyl]-, diethyl ester(50375-72-9)
• EPA Substance Registry System: Phosphonic acid, [(2-hydroxyphenyl)methyl]-, diethyl ester(50375-72-9)

Safety Data

• Hazardous Substances Data: 50375-72-9(Hazardous Substances Data)

Upstream product

• 90-01-7 salicylic alcohol 
• 122-52-1 triethyl phosphite 
• 40053-98-3 o-chloromethyl phenol 

Downstream Products

• 410092-69-2 Diethyl tosyloxy(m-nitrobenzyl)phosphonate 

Relevant articles and documents

Synthesis of acyclic and cyclic phosphonates based on substituted 2-hydroxybenzylic alcohols

A convenient synthesis of benzylic phosphonates and 2,3-dihydrobenzo[d][1,2]oxaphosphole 2-oxides substituted at the aromatic ring, as well as their precursors, 2-hydroxybenzylic alcohols, from the derivatives of salicylic aldehyde, salicylic acid, and 2-hydroxyacetophenone bearing an additional hydroxy or methoxy group at the para position of the aromatic ring was developed. For the first time, the possibility of selective demethylation of the methoxy group positioned ortho to the methylene phosphonate fragment with retention of the methoxy group at the para position was shown.

Organocatalytic Phosphonylation of in Situ Formed o-Quinone Methides

A new class of Br?nsted acid catalysts based on N-heterocyclic phosphorodiamidic acids (NHPAs) has been developed. The NHPA catalyst promotes phospha-Michael addition reaction of trialkylphosphites to in situ generated ortho-quinone methides (o-QMs) for t

Immonium salts and derivatives thereof

There are provided: novel aryloxy immonium salts, prepared by the reaction of their corresponding haloformates with amides; and phenolic compositions corresponding to the aryloxy immonium salts. These novel aryloxy immonium salts and their corresponding phenolic compositions have utility as chemical intermediates, antioxidants, stabilizers and antibacterials.