50399-51-4

Basic information

• Product Name: 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine
• CAS NO: 50399-51-4
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.2429
• Mol File: 50399-51-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 288.752°C at 760 mmHg
• Flash Point: 130.883°C
• Density: 1.056g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine(50399-51-4)
• EPA Substance Registry System: 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine(50399-51-4)

Safety Data

• Hazardous Substances Data: 50399-51-4(Hazardous Substances Data)

Usage

General Description

7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine is a chemical compound that belongs to the amine class of organic compounds. It is a derivative of naphthalene, containing a methoxy group and an amine group. 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine is commonly used in research and pharmaceutical applications, particularly in the development of neurotransmitter modulators and potential therapeutic drugs. Additionally, it may also have various industrial and commercial uses due to its unique chemical properties. Overall, 7-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine plays a crucial role in the development of new drugs and understanding various biological processes.

Upstream product

• 20175-97-7 7-methoxy-3,4-dihydronaphthalen-1(2H)-one oxime 
• 6836-19-7 7-Methoxy-1-tetralone 
• 305797-92-6 C₁₆H₂₃NO₃ 

Downstream Products

• 175357-87-6 N-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)diphenylacetamide 

Relevant articles and documents

ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT

The present invention concerns a compound of following general formula (I): where: either R is an R1 group and R′ is an -A1-Cy1 group, or R is an -A1-Cy1 group and R′ is an R1 group, R1 particularly being H or (C1-C6)alkyl group;A1 being an —NH— radical or —NH—CH2— radical;Cy1 particularly being a phenyl group,A is a fused (hetero)aromatic ring having 5 to 7 atoms, for use for treating cancer.

Synthesis and evaluation of dimeric 1,2,3,4-Tetrahydro-naphthalenylamine and Indan-1-ylamine derivatives with mast cell-stabilising and anti-allergic activity

In a continuation of our studies into 4-Amino-3,4-dihydro-2H-naphthalen-1-ones as novel modulators of allergic and inflammatory phenomena, we have extended our work to include dimeric analogues. Of these derivatives, the most promising activity was seen with tertiary amine 58a, which exhibited potent mast cell-stabilising activity in vitro against a variety of stimuli and also in vivo against passive cutaneous anaphylaxis.

HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention relates to novel hydroxyethylamine compounds of formula (I): (I) having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated-amyloid levels or-amyloid deposits, particularly Alzheimer's disease.