50442-68-7

Basic information

• Product Name: 6-hydroxy-4,4,5,7-tetramethyl-3,4-dihydrocoumarin
• Synonyms: 6-hydroxy-4,4,5,7-tetramethyl-3,4-dihydrocoumarin
• CAS NO: 50442-68-7
• Molecular Weight: 220.268
• Mol File: 50442-68-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-hydroxy-4,4,5,7-tetramethyl-3,4-dihydrocoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxy-4,4,5,7-tetramethyl-3,4-dihydrocoumarin(50442-68-7)
• EPA Substance Registry System: 6-hydroxy-4,4,5,7-tetramethyl-3,4-dihydrocoumarin(50442-68-7)

Safety Data

• Hazardous Substances Data: 50442-68-7(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 133544-77-1 3-(3',6'-Dioxo-2',4'-dimethylcyclohexa-1',4'-dienyl)-3,3-dimethylpropionic acid 

Downstream Products

• 133544-77-1 3-(3',6'-Dioxo-2',4'-dimethylcyclohexa-1',4'-dienyl)-3,3-dimethylpropionic acid 
• 1381849-15-5 C₅₁H₅₃FN₃O₉P 
• 1381849-14-4 C₅₇H₆₇FN₃O₉PSi 
• 1381849-13-3 3-(6-((bis(benzyloxy)phosphoryl)oxy)-3-((tert-butyldimethylsilyl)oxy)-2,4-dimethylphenyl)-3-methylbutanoic acid 
• 1381849-12-2 dibenzyl (4-((tert-butyldimethylsilyl)oxy)-3,5-dimethyl-2-(2-methyl-4-oxobutan-2-yl)phenyl)phosphate 
• 1381849-11-1 dibenzyl (4-((tert-butyldimethylsilyl)oxy)-2-(4-hydroxy-2-methylbutan-2-yl)-3,5-dimethylphenyl)phosphate 
• 1381849-10-0 4-((tert-butyldimethylsilyl)oxy)-2-(4-hydroxy-2-methylbutan-2-yl)-3,5-dimethylphenol 
• 121031-06-9 N,N-dimethyl-β,β,2,4-tetramethyl-5-(N-methylamino)-3,6-dioxo-1,4-cyclohexadiene-1-propanamide 
• 121031-02-5 β,β,2,4-tetramethyl-5-(N-methylamino)-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid 
• 203856-42-2 terephthalic acid 1-methyl ester 4-(2,4,4,5,7-pentamethyl-4H-chromen-6-yl) ester 
• 264888-41-7 6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid 3-(3-benzyloxy-6-hydroxy-2,4-dimethyl-phenyl)-3-methyl-butyl ester 
• 264888-37-1 2-tert-butoxycarbonylamino-3-(1-formyl-1H-indol-3-yl)-propionic acid 3-(3-benzyloxy-6-hydroxy-2,4-dimethyl-phenyl)-3-methyl-butyl ester 

Relevant articles and documents

Reductive and Bioreductive Activation is Controlled by Electronic Properties of Substituents in Conformationally-Constrained Anticancer Drug Delivery Systems

Conformationally-constrained, anticancer drug delivery systems (TDDS) containing the methyl ester of melphalan (as a model drug) were synthesized using electron-withdrawing or electron-donating functional groups to modulate reductive and bioreductive activation. The electronic nature of substituents in TDDS was found to control reductive and bioreductive activation of TDDS, thus influencing drug delivery from TDDS.