50463-17-7

Basic information

• Product Name: 2-(prop-2-en-1-ylsulfanyl)-1,3-benzoxazole
• Synonyms: 2-(Allylsulfanyl)-1,3-benzoxazole; benzoxazole, 2-(2-propen-1-ylthio)-
• CAS NO: 50463-17-7
• Molecular Formula: C₁₀H₉NOS
• Molecular Weight: 191.2496
• Mol File: 50463-17-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 286.5°C at 760 mmHg
• Flash Point: 127.1°C
• Density: 1.21g/cm³
• Vapor Pressure: 0.00453mmHg at 25°C
• Refractive Index: 1.631
• CAS DataBase Reference: 2-(prop-2-en-1-ylsulfanyl)-1,3-benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(prop-2-en-1-ylsulfanyl)-1,3-benzoxazole(50463-17-7)
• EPA Substance Registry System: 2-(prop-2-en-1-ylsulfanyl)-1,3-benzoxazole(50463-17-7)

Safety Data

• Hazardous Substances Data: 50463-17-7(Hazardous Substances Data)

Usage

General Description

2-(prop-2-en-1-ylsulfanyl)-1,3-benzoxazole is a chemical compound with the molecular formula C11H9NOS. It is a benzoxazole derivative, which comprises a benzene ring fused to an oxazole ring with a thioether substituent at the 2-position. 2-(prop-2-en-1-ylsulfanyl)-1,3-benzoxazole is commonly used in the synthesis of pharmaceuticals, agrochemicals, and organic materials. It has also been studied for its potential pharmacological properties, including its role as an antifungal and antibacterial agent. Additionally, it is a valuable building block in organic chemistry, as it can be used in various synthetic reactions to create new and complex molecules.

Upstream product

• 35466-83-2 allyl methyl carbonate 
• 2382-96-9 2-sulfanyl-1,3-benzoxazole 
• 2382-96-9 benzo[d]oxazole-2-(3H)-thione 
• 51389-04-9 2-(allylthio)-1H-benzimidazole 
• 67-66-3 chloroform 
• 106-95-6 allyl bromide 
• 19172-47-5 Lawessons reagent 
• 3116-52-7 N,N'-diisopropyl-O-allylisourea 
• 97-74-5 bis(dimethylthiocarbamoyl)sulfide 
• 95-55-6 2-amino-phenol 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 273-53-0 benzoxazole 
• 2179-57-9 diallyl disulphide 

Relevant articles and documents

Synthesis, characterization, and preliminary in vitro cytotoxic evaluation of a series of 2-substituted benzo [d] [1,3] azoles

A series of benzo [d] [1,3] azoles 2-substituted with benzyl-and allyl-sulfanyl groups were synthesized, and their cytotoxic activities were in vitro evaluated against a panel of six human cancer cell lines. The results showed that compounds BTA-1 and BMZ

A novel synthesis of 2-alkylthiobenzothiazoles and 2-alkylthiobenzoxazoles

3H-Benzothiazole-2-thione and 3H-benzoxazole-2-thione were selectively S-alkylated by use of O-alkylisoureas as the alkylating reagents. The reactions could be performed under mild reaction conditions in short reaction times, and high yields were obtained using O-primary-alkylisoureas, whereas low yields were obtained with sec-and tert-alkylisoureas.

Reactions of 2-allylthiobenzimidazole, -oxazole, -thiazole, and the isomeric thiones with dichlorocarbene

The reactions of 2-allylthiobenzimidazole, -oxazole, and -thiazole, and the thiones formed from them on heating, with dichlorocarbene have been investigated under phase transfer catalysis conditions.