50463-82-6

Basic information

• Product Name: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate
• CAS NO: 50463-82-6
• Molecular Weight: 233.267
• Mol File: 50463-82-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate(50463-82-6)
• EPA Substance Registry System: (2R)-(+)-phenylmethyl 2-formylpyrrolidine-1-carboxylate(50463-82-6)

Safety Data

• Hazardous Substances Data: 50463-82-6(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 200499-57-6 (2R,4'S)-N-Benzyloxycarbonyl-2-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)pyrrolidine 
• 200499-52-1 (R)-4-Azido-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester 
• 200499-54-3 (R)-4-Azido-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyraldehyde 
• 200499-55-4 (R)-2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrrolidine 
• 136963-32-1 methyl 2,3-dideoxy-5,6-O-isopropylidene-4-O-p-tolylsulfonyl-D-erythro-hexonate 
• 68832-13-3 D-prolinol 
• 200499-58-7 (R)-1-benzyloxycarbonyl-2-[(S)-1,2-dihydroxyethyl]pyrrolidine 
• 182210-00-0 methyl (2R)-(benzyloxycarbonyl)pyrrolidine-2-carboxylate 
• 72597-18-3 (2R)-(+)-phenylmethyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 146727-84-6 benzyl (2R)-2-((1E)-3-ethoxy-3-oxoprop-1-enyl)pyrrolidine-1-carboxylate 
• 259868-85-4 methyl (R)-3-[1-(benzyloxycarbonyl)pyrrolidin-2-yl]acrylate 
• 953429-99-7 C₁₆H₂₂NO₉P 
• 1036404-01-9 (R)-(N-benzyloxycarbonyl)-2-(2-oxoethyl)pyrrolidine 
• 1327157-87-8 (R)-benzyl 2-((R)-1-hydroxypent-4-en-1-yl)pyrrolidine-1-carboxylate 
• 1403231-83-3 (R)-benzyl 2-((S)-1-hydroxypent-4-en-1-yl)pyrrolidine-1-carboxylate 

Relevant articles and documents

FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

INDANOL DERIVATIVE

The present invention provides a compound having the following general formula (I) which is useful as a neurokinin receptor antagonist: (wherein, R1, R2: optionally substituted (hetero)aryl, R3: -CO-R4, -CO-O-R4, etc., R4: alkyl, cycloalkyl, etc., A: CH2, CO, SO2, B: a single bond, etc., D: oxygen, CH2, E: alkylene, alkenylene, n: 1 to 3).

New highly potent GABA uptake inhibitors selective for GAT-1 and GAT-3 derived from (R)- and (S)-proline and homologous pyrrolidine-2-alkanoic acids

We synthesized proline and pyrrolidine-2-alkanoic acid derivatives in their enantiomerically pure form and evaluated them for their affinity to the GABA transport proteins GAT-1 and GAT-3. Among the compounds presented herein, (R)-pyrrolidine-2-acetic aci