50483-71-1Relevant articles and documents
Multicomponent reactions (MCRs) of arylmethyl bromides, arylamidines and elemental sulfur toward unsymmetric 3,5-diaryl 1,2,4-thiadiazoles
Zhou, Zhen,Liu, Miaochang,Sun, Song,Yao, En,Liu, Suqin,Wu, Zhiwen,Yu, Jin-Tao,Jiang, Yan,Cheng, Jiang
, p. 2571 - 2573 (2017)
A base-promoted three-component reaction between arylmethyl bromides, arylamidines and elemental sulfur was developed, leading to unsymmetric 3,5-diaryl-1,2,4-thiadiazoles in moderate to good yields with chemical diversity and complexity. This procedure shows broad substrates scope by employing elemental sulfur and commercially available starting materials under transition-metal free conditions.