505-48-6 Usage
Description
It was firstly produced by nitric acid oxidation of cork (Latin suber) material and then from castor oil. The oxidation of ricinoleic acid produces, by splitting at the level of the double bond and at the level of the OH group, at the same time, suberic acid (octanedioic acid) and the next homologue azelaic acid. Suberic acid was used in the manufacture of alkyd resins and in the synthesis of polyamides leading to nylon.
Chemical Properties
off-white crystalline powder
Uses
Different sources of media describe the Uses of 505-48-6 differently. You can refer to the following data:
1. Suberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluoresc
ent detection of amidinium-carboxylate and amidinium formation.
2. In the plastics industry.
3. Suberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluorescent detection of amidinium-carboxylate and amidinium formation.
Definition
ChEBI: An alpha,omega-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane.
Synthesis Reference(s)
Journal of the American Chemical Society, 81, p. 3677, 1959 DOI: 10.1021/ja01523a046
Purification Methods
Crystallise it from acetone. It sublimes at 300o without decomposition. [Beilstein 2 IV 2028.]
Check Digit Verification of cas no
The CAS Registry Mumber 505-48-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 505-48:
(5*5)+(4*0)+(3*5)+(2*4)+(1*8)=56
56 % 10 = 6
So 505-48-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H14O4/c9-7(10)5-3-1-2-4-6-8(11)12/h1-6H2,(H,9,10)(H,11,12)/p-2
505-48-6Relevant articles and documents
Vesonder,R.F. et al.
, p. 2029 - 2032 (1971)
A direct synthesis of carboxylic acidsviaplatinum-catalysed hydroxycarbonylation of olefins
Schneider, Carolin,Franke, Robert,Jackstell, Ralf,Beller, Matthias
, p. 2703 - 2707 (2021/05/05)
The platinum-catalysed hydroxycarbonylation of olefins is reported for the first time. Using a combination of PtCl2/2,2′-bis(tert-butyl(pyridin-2-yl)phosphanyl)-1,1′-binaphthalene (Neolephos) in the presence of sulfuric acid [0.6 M] in acetic acid selective carbonylation of terminal aliphatic olefins proceeds to good yields and selectivities to the corresponding carboxylic acids. Comparing the reactivity of different butenes (iso- andn-butenes), the terminal olefin can be selectively carbonylated.
A mild reaction conditions of the catalytic oxidation of cyclooctane new method (by machine translation)
-
Paragraph 0023-0024; 0037-0038, (2019/03/28)
A cyclooctane catalytic oxidation method, said method comprising: the metal porphyrin, cyclooctane mixing, at a temperature of 80 - 120 °C, O2 The pressure 0.6 - 2 mpa reaction under the condition of 2 - 48 H-, after processing reaction liquid, separating the oxidation product [...], cyclooctanol, ring octanone; the invention relates to a new method of cyclooctane catalytic oxidation reaction temperature is low, the catalyst amount is less, but in order to O2 As the oxidizing agent, environmental protection, cyclooctane can be the highly selective oxide cyclooctanol, ring octanone and [...], the catalytic oxidation of cyclooctane new method also has the simple operation, does not use an organic solvent, ring octanone selectivity and the like. (by machine translation)