505088-49-3Relevant articles and documents
Silver-Catalyzed Site-Selective Ring-Opening and C-C Bond Functionalization of Cyclic Amines: Access to Distal Aminoalkyl-Substituted Quinones
Liu, Rui-Hua,He, Yi-Heng,Yu, Wei,Zhou, Bo,Han, Bing
, p. 4590 - 4594 (2019)
Distal aminoalkyl-substituted quinones have been efficiently prepared through silver-catalyzed site-selective deconstruction and C-C bond transformation of unstrained N-acylated cyclic amines. This method enjoys mild reaction conditions, high selectivity, a broad scope of substrates, and a low catalytic loading of silver. This strategy can also be applied to the modification of peptides bearing cyclic amine residues.