50530-16-0

Basic information

• Product Name: <7-13C>cyclohexanecarboxylic acid
• Synonyms: <7-13C>cyclohexanecarboxylic acid
• CAS NO: 50530-16-0
• Molecular Weight: 129.16
• Mol File: 50530-16-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: <7-13C>cyclohexanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: <7-13C>cyclohexanecarboxylic acid(50530-16-0)
• EPA Substance Registry System: <7-13C>cyclohexanecarboxylic acid(50530-16-0)

Safety Data

• Hazardous Substances Data: 50530-16-0(Hazardous Substances Data)

Upstream product

• 108-85-0 1-bromocyclohexane 
• 1111-72-4 carbon dioxide 
• 98-89-5 Cyclohexanecarboxylic acid 
• 542-18-7 cyclohexyl chloride 
• 110-83-8 cyclohexene 
• 931-50-0 cyclohexylmagnesium bromide 
• 1641-69-6 [13C]Carbon monoxide 

Downstream Products

• 349651-62-3 C₉⁽¹³⁾C₂H₁₈O₂ 
• 349651-63-4 C₇⁽¹³⁾C₂H₁₅Br 
• 87803-56-3 C₆⁽¹³⁾CH₁₂O 

Relevant articles and documents

Synthesis of Carbon-13 Labelled Carboxylic Acids via Organoborane Reactions

13C-Labelled carboxylic acids are readily synthesized via the reaction of organoboranes with 13C-enriched carbon monoxide; functionally substituted acids are efficiently prepared via a carbonylation-oxidation sequence.

Catalytic Decarboxylation/Carboxylation Platform for Accessing Isotopically Labeled Carboxylic Acids

An integrated catalytic decarboxylation/carboxylation for accessing isotopically labeled carboxylic acids with13CO2 or14CO2 is described. The method shows a wide scope under mild conditions, even in the context of late-stage functionalization, and does not require stoichiometric organometallics, thus complementing existing carbon-labeling techniques en route to carboxylic acids.

Biosynthesis of phoslactomycins: Cyclohexanecarboxylic acid as the starter unit

Phoslactomycins (PLMs) A-F, produced by actinomycetes are polyketide-type antibiotics derived from a hydroxycyclohexanecarboxylic acid or a cyclohexanecarboxylic acid starter unit. Feeding experiments with [2- 13C]shikimic acid indicated that the C-18 carbon of PLMs comes from C-5 of shikimate. Further feeding studies of cis and trans-3-hydroxy[7- 13C]cyclohexanecarboxylic acid, [7-13C]- and [ 2H11]cyclohexanecarboxylic acid have suggested that the starter unit in the PLM biosynthesis is not cis-3-hydroxycyclohexanecarboxylate but cyclohexanecarboxylate and that PLM-B is produced initially, and subsequently converted to other analogs by hydroxylation and acylation.