50534-13-9

Basic information

• Product Name: 4-[[7-chloro-4-quinolinyl]amino]benzoic acid
• Synonyms: 4-[[7-chloro-4-quinolinyl]amino]benzoic acid
• CAS NO: 50534-13-9
• Molecular Weight: 298.729
• Mol File: 50534-13-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[[7-chloro-4-quinolinyl]amino]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[[7-chloro-4-quinolinyl]amino]benzoic acid(50534-13-9)
• EPA Substance Registry System: 4-[[7-chloro-4-quinolinyl]amino]benzoic acid(50534-13-9)

Safety Data

• Hazardous Substances Data: 50534-13-9(Hazardous Substances Data)

Upstream product

• 86-98-6 4,7-dichloroquinoline 
• 99-05-8 meta-aminobenzoic acid 
• 150-13-0 4-amino-benzoic acid 
• 150514-38-8 4-[(7-Chloro-4-quinolinyl)amino]benzoic acid methyl ester hydrochloride 

Downstream Products

• 1446787-08-1 [4-(7-chloro-quinolin-4-ylamino)-phenyl]-(4-methylpiperidin-1-yl)-methanone 
• 1446787-09-2 [4-(7-chloro-quinolin-4-ylamino)-phenyl]-(4-ethylpiperazin-1-yl)-methanone 
• 1446787-10-5 [4-(7-chloro-quinolin-4-ylamino)-phenyl]-pyrrolidin-1-yl-methanone 
• 1446787-11-6 [4-(7-chloro-quinolin-4-ylamino)-phenyl]-(2-methylpiperidin-1-yl)-methanone 
• 150514-39-9 N-(1-Butyl-4-piperidinyl)-4-[(7-chloro-4-quinolinyl)amino]benzamide 
• 55121-95-4 7-Chloro-4-<4-(N-phenylpiperazinocarbonyl)-phenyl>aminoquinoline 
• 25143-11-7 [4-(7-chloro-quinolin-4-ylamino)-phenyl]-(4-methylpiperazin-1-yl)-methanone 
• 108199-09-3 4-[4-(7-chloro-quinolin-4-ylamino)-benzoyl]-morpholine 

Relevant articles and documents

Synthesis and in vitro cytotoxic evaluation of 7-chloro-4-anilino-quinoline amide derivatives

A series of new amide derivatives of 4-anilino-quinoline have been synthesized and evaluated in vitro cytotoxic activity against the human hepatocellular carcinoma (HepG2), human lung carcinoma (SK-LU-1) and human breast cancer (MCF-7). Compound 5g was found to be most potent cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 2.09 and 4.63 μg/mL, respectively. Compound 5e exhibited significant cytotoxic activity against three cell lines with IC50 values ranging from 5-10 μg/mL.