50543-56-1Relevant articles and documents
Method for synthesizing 2-aryl benzofuran and derivatives thereof
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Paragraph 0029-0032, (2020/05/08)
The invention relates to a method for synthesizing 2-aryl benzofuran and derivatives thereof. According to the method, cheap and easily available 2, 3-dihydrobenzofuran compounds, an organic boron reagent and bromo-aromatic hydrocarbon are taken as raw materials, and a two-step cascade reaction is carried out under mild conditions, so that the 2-aryl benzofuran product can be conveniently prepared. At present, the reported synthesis methods of 2-aryl benzofuran and derivatives thereof mainly have the problems of long synthesis route, expensive raw materials, harsh reaction conditions and the like. Compared with reported methods, the synthesis method has the advantages of specific reaction selectivity, short reaction route and the like, and a convenient and efficient synthesis strategy is provided for laboratory preparation or industrial production of 2-arylbenzofuran products.
One-pot synthesis of substituted benzo[b]furans from mono- and dichlorophenols using palladium catalysts bearing dihydroxyterphenylphosphine
Yamaguchi, Miyuki,Katsumata, Haruka,Manabe, Kei
, p. 9270 - 9281 (2013/10/08)
A dihydroxyterphenylphosphine bearing cyclohexyl groups on the phosphorus atom (Cy-DHTP) was found to be a powerful ligand for the palladium-catalyzed one-pot synthesis of substituted benzo[b]furans from 2-chlorophenols and terminal alkynes. This catalyst
