50584-02-6

Basic information

• Product Name: trans-2-Benzamido-1-phenyl-cyclopropan
• Synonyms: trans-2-Benzamido-1-phenyl-cyclopropan
• CAS NO: 50584-02-6
• Molecular Weight: 237.301
• Mol File: 50584-02-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-2-Benzamido-1-phenyl-cyclopropan(CAS DataBase Reference)
• NIST Chemistry Reference: trans-2-Benzamido-1-phenyl-cyclopropan(50584-02-6)
• EPA Substance Registry System: trans-2-Benzamido-1-phenyl-cyclopropan(50584-02-6)

Safety Data

• Hazardous Substances Data: 50584-02-6(Hazardous Substances Data)

Upstream product

• 1036637-32-7 methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate 
• 100-42-5 styrene 
• 95-62-5 (1R,2S)-1-amino-2-phenylcyclopropane 
• 98-88-4 benzoyl chloride 
• 874341-82-9 [(1S,2R)-2-nitrocyclopropyl]benzene 
• 155-09-9 trans-2-phenylcyclopropylamine 
• 54-97-7 rac-cis-2-phenylcyclopropan-1-amine 

Relevant articles and documents

Catalytic asymmetric synthesis of nitrocyclopropane carboxylates

A Cu(I)-catalyzed asymmetric cyclopropanation of alkenes with an iodonium ylide has been developed. The copper source, hypervalent iodine source, solvent, and additives all have a significant effect on the yields and enantioselectivities. High enantioselectivity (up to 99:1 er) and diastereoselectivity (95:5 dr trans/cis) were achieved for a wide range of alkenes. Conditions were developed to convert the trans products to the cis isomers. In addition, 1-nitrocyclopropyl carboxylates were transformed into the corresponding substituted cyclopropane amino acids and aminocyclopropanes. Moreover, a comparative study between Zn- and In-mediated reduction reactions of the nitro group in these compounds with regards to the er erosion in the process is also documented.