50586-80-6

Basic information

• Product Name: m-PEG3-Tos
• Synonyms: m-PEG3-Tos;Ethanol, 2-(2-methoxyethoxy)-, 4-methylbenzenesulfonate
• CAS NO: 50586-80-6
• Molecular Formula: C₁₂H₁₈O₅S
• Molecular Weight: 274.33332
• Mol File: 50586-80-6.mol
• Article Data: 106

Chemical Properties

• Boiling Point: 392.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.179±0.06 g/cm3(Predicted)
• CAS DataBase Reference: m-PEG3-Tos(CAS DataBase Reference)
• NIST Chemistry Reference: m-PEG3-Tos(50586-80-6)
• EPA Substance Registry System: m-PEG3-Tos(50586-80-6)

Safety Data

• Hazardous Substances Data: 50586-80-6(Hazardous Substances Data)

Usage

Description

m-PEG3-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Upstream product

• 71776-35-7 {3'-Hydroxymethyl-2,2'-bis-[2-(2-methoxy-ethoxy)-ethoxy]-[1,1']binaphthalenyl-3-yl}-methanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 112-35-6 triethylene glucol monomethyl ether 
• 111-90-0 ethoxyethoxyethanol 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 87104-88-9 2-Phenyl-5,5-bis(2,5,8-trioxanonyl)-1,3-dioxan 
• 112968-89-5 1-bromo-4-[2-(2-methoxyethoxy)ethoxy]benzene 
• 87104-99-2 9-Benzyloxymethyl-2,5,8,11,14,17-hexaoxaoctadecan 
• 87104-93-6 10-Benzyloxymethyl-10-methyl-2,5,8,12,15,18-hexaoxanonadecan 
• 87105-02-0 10-Benzyloxymethyl-2,5,8,12,15,18-hexaoxanonadecan 
• 123852-07-3 N,N bis(triethyleneglycol-monomethylether)tritylamine 
• 104144-33-4 C₂₈H₄₂O₈ 
• 123-91-1 1,4-dioxane 
• 67-56-1 methanol 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 104539-21-1 2-(2-methoxyethoxy)ethyl iodide 
• 215181-61-6 1-(1-ethoxy-2-azido)-2-methoxyethane 
• 123852-09-5 N,N bis(diethyleneglycol-monomethylether)benzylamine 
• 344319-41-1 2-Phenyl-5-(2,5,8-trioxanonyl)-1,3-dioxan 

Relevant articles and documents

Change in the rate of pseudo[1]rotaxane formation by elongating the alkyl-chain-substituted diphenylethynylene linked to permethyl α-cyclodextrin

Herein, we report the kinetics of pseudo[1]rotaxane formation from permethyl α-cyclodextrin attached to a flexible-chain-substituted diphenylethynylene. When the chain is an alkyl group, the rate of formation shows different trends over three regions of chain length: deceleration (chain length = 1–3), acceleration (4–8), and re-deceleration (>12). This behavior is driven by a relative decrease in the ΔH? of the transition.

A water/alcohol-soluble conjugated porphyrin small molecule as a cathode interfacial layer for efficient organic photovoltaics

A water/alcohol soluble conjugated porphyrin small molecule, FNEZnP-OE, in which two amino-functionalized fluorenes (9,9-bis(30-(N,N-dimethylamino)propyl)-2,7-fluorenes) are linked to a porphyrin core substituted with two polar 3,4-bis-[2-(2-methoxy-ethoxy)-ethoxy]-phenyls by ethynylene linkages, is designed and synthesized as a cathode interfacial material (CIM) for bulk heterojunction organic solar cells. The PTB7/PC71BM- and PTB7-Th/PC71BM-based devices with FNEZnP-OE as the electron transport layers (ETLs) exhibit power conversion efficiencies (PCEs) of 8.52% and 9.16%, respectively, which are increased by 47% and 41% compared to the devices with no ETL (5.78% and 6.50%, respectively). Most significantly, these PCEs are increased by 13.6% and 8%, respectively, over those with the widely used polymer ETL PFN (poly[(9,9-bis(30-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-ioctylfluorene)]). The outstanding performance of FNEZnP-OE CIM is contributed by not only the polar groups of 9,9-bis(30-(N,N-dimethylamino)propyl)-2,7-fluorenes and 3,4-bis-[2-(2-methoxy-ethoxy)-ethoxy]-phenyls but also the porphyrin-relating π-conjugated backbone of FNEZnP-OE induced by the ethynylene linkages, demonstrating that functionalized porphyrins are very promising interfacial materials.

A lysosome-targetable fluorescent probe for real-time imaging cysteine under oxidative stress in living cells

As an effective lysosomal biomarker for oxidative stress status, cysteine (Cys)plays an important role in lysosomal proteolysis. Herein, we report the first lysosome-targetable fluorescence probe (MCAB)for Cys-selective detection based on nucleophilic add

Cyanine fluorophores for cellular protection against ROS in stimulated macrophages and two-photon ROS detection

We report the first example of a novel two-photon active, biocompatible, and macrophage cell-membrane permeable carbazole-based cyanine fluorophore for the detection of three biologically important ROS, namely, ?OH, O2- and OCl- in solution. This versatile probe shows cellular protection not only in stimulated macrophages from phorbol-12-myristate-13-acetate-induced morphological changes but also lipopolysaccharide-induced cytotoxicity by quenching with the O2- and OCl- production, respectively. Such protection could be visualized by a distinct change in the fluorescence intensity of the probe.

Self-assembly, conductivity and chemosensor behavior of biphenylsulfone based Janus polycatenar

A novel Janus polycatenar JP-I bearing a bisphenylsulfone central core, with a hydrophobic 3,4,5-tridodecyloxybenzylether unit at one side and a hydrophilic trioligoethylene oxide benzyl triazoly unit at another side has been synthesized via copper(I)-cat

Ratiometric emission NIR-fluorescent probe for the detection of lysosomal pH in living cells and: In vivo

The lysosome is known to be an acidic organelle that is ubiquitous in cells. Acidic pH is a characteristic feature of lysosomes, and aberrant lysosomal pH values have been manifested to be associated with diverse diseases. In order to monitor the lysosoma

Preparation, Photophysical and Electrochemical Evaluation of an Azaborondipyrromethene/Zinc Porphyrin/Graphene Supramolecular Nanoensemble

The preparation of an entirely supramolecular, multichromophoric azaborondipyrromethene (ABDP)/zinc tetraphenylporphyrin (ZnTPP)/exfoliated graphene (GR) nanoensemble was accomplished. The ABDP derivative bears glycol chains for enhancing solubility and a

A New Class of Ionically Conducting Fluorinated Ether Electrolytes with High Electrochemical Stability

Increasing battery energy density is greatly desired for applications such as portable electronics and transportation. However, many next-generation batteries are limited by electrolyte selection because high ionic conductivity and poor electrochemical st

New highly soluble triarylamine-based materials as promising catholytes for redox flow batteries

A series of arylamines bearing oligoethylene glycol ether solubilizing moieties were designed and comprehensively evaluated as promising catholyte materials for non-aqueous redox flow batteries (RFBs). The triphenylamine core maintains the chemical stability of the radical cation, the ethylene glycol chains enhance the solubility up to complete miscibility with organic solvents, and the electron-withdrawing bromine substituents increase the redox potential of the compounds up to 0.61 Vvs.Ag/AgNO3. The best material showed 99% coulombic efficiency in combination with good stability in over 50 charge-discharge cycles in laboratory RFB cells. The designed triarylamine-based catholyte materials appear promising for the development of next-generation high-voltage and high-capacity RFBs.