506-31-0

Basic information

• Product Name: 9-Eicosenoic acid
• Synonyms: icos-9-enoic acid;9-EICOSENOIC ACID;(E)-icos-9-enoic acid;9-Icosenoic acid;(E)-9-Eicosenoic acid;(E)-9-Icosenoic acid
• CAS NO: 506-31-0
• Molecular Formula: C20H38O2
• Molecular Weight: 310.51
• EINECS: 208-032-9
• Mol File: 506-31-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 23°C
• Boiling Point: 419.84°C (estimate)
• Flash Point: 299.5 °C
• Appearance: /
• Density: 0.8882
• Vapor Pressure: 1.3E-07mmHg at 25°C
• Refractive Index: 1.4597
• PKA: 4.78±0.10(Predicted)
• CAS DataBase Reference: 9-Eicosenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Eicosenoic acid(506-31-0)
• EPA Substance Registry System: 9-Eicosenoic acid(506-31-0)

Safety Data

• Hazardous Substances Data: 506-31-0(Hazardous Substances Data)

Usage

General Description

9-Eicosenoic acid, also known as Gondoic acid, is a monounsaturated omega-9 fatty acid with a 20-carbon chain and one double bond at the 9th carbon from the omega end. It is commonly found in the oils of several plant sources such as safflower, wheat germ, and sea buckthorn. This acid has been identified as a potential biomarker for certain diseases, including autism and cardiovascular diseases. Studies have suggested potential health benefits of 9-eicosenoic acid, including its anti-inflammatory and antioxidant properties, as well as its role in improving lipid metabolism and reducing the risk of cardiovascular diseases. It is also used in the cosmetic industry for its moisturizing and nourishing properties when applied topically.

InChI:InChI=1/C20H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h11-12H,2-10,13-19H2,1H3,(H,21,22)/b12-11+

Upstream product

• 116557-14-3 eicos-9c-enoic acid ethyl ester 
• 112-44-7 undecylaldehyde 
• 8001-23-8 safflower oil 
• 26825-92-3 methyl 8-bromooctanoate 
• 1309764-97-3 methyl icos-9-ynoate 
• 67810-35-9 cis-Eicos-9-enoic acid methyl ester 
• 17696-11-6 8-bromooctanoic acid 
• 29204-02-2 gadoleic acid 

Downstream Products

• 62133-71-5 eicos-9t-enoic acid 
• 60-33-3 linoleic acid 

Relevant articles and documents

A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration

Neuropathic pain (NP) is a complex chronic pain state with a prevalence of almost 10% in the general population. Pharmacological options for NP are limited and weakly effective, so there is a need to develop more efficacious NP attenuating drugs. Activation of the type 1 lysophosphatidic acid (LPA1) receptor is a crucial factor in the initiation of NP. Hence, it is conceivable that a functional antagonism strategy could lead to NP mitigation. Here we describe a new series of LPA1 agonists among which derivative (S)-17 (UCM-05194) stands out as the most potent and selective LPA1 receptor agonist described so far (Emax = 118%, EC50 = 0.24 μM, KD = 19.6 nM; inactive at autotaxin and LPA2-6 receptors). This compound induces characteristic LPA1-mediated cellular effects and prompts the internalization of the receptor leading to its functional inactivation in primary sensory neurons and to an efficacious attenuation of the pain perception in an in vivo model of NP.

NEW CONJUGATED LINOLENIC ACIDS AND METHODS FOR COMMERCIAL PREPARATION AND PURIFICATION

A method for the preparation and purification of conjugated linolenic acids is described. The method comprises blending a mixture of vegetable oils and or fats including various concentrations of alpha or gamma and or both linolenic acids with a base. The method transforms approximately over two thirds of α-linolenic acid (9Z,12Z,15Z-octadecatrienoic acid) into 9Z,11E,15Z-octadecatrienoic acid and 9Z,13E,15Z-octadecatrienoic acid. The method also transforms gamma-linolenic acid (6Z,9Z,12Z-octadecatrienoic acid) into 6Z,8E,15Z-octadeccatrienoic acid and 6Z,10E,12Z-octadecatrienoic acid. In all cases, geometrical isomers and fully conjugated isomers are also produced.