50615-16-2

Basic information

• Product Name: SODIUM METHANETHIOLATE
• Synonyms: METHYL MERCAPTAN SODIUM SALT;METHANETHIOL SODIUM SALT;SODIUM METHYL SULFIDE;SODIUM METHYL MERCAPTIDE;2-methyl-6,7-dihydro-1-benzofuran-4(5H)-one(SALTDATA: 1.5H2O);2-methyl-6,7-dihydrobenzofuran-4(5H)-one;2-methyl-6,7-dihydro-1-benzofuran-4(5H)-one
• CAS NO: 50615-16-2
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 70.09
• EINECS: 225-969-9
• Mol File: 50615-16-2.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 256.7oC at 760 mmHg
• Flash Point: 27 °C
• Appearance: /
• Density: 1.139g/cm3
• Vapor Pressure: 0.0151mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: SODIUM METHANETHIOLATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM METHANETHIOLATE(50615-16-2)
• EPA Substance Registry System: SODIUM METHANETHIOLATE(50615-16-2)

Safety Data

• Hazard Codes: C
• Statements: 31-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3263 8/PG 3
• WGK Germany: 3
• F: 1-34-10-13
• Hazardous Substances Data: 50615-16-2(Hazardous Substances Data)

Usage

Description

Sodium methanethiolate, also known as sodium methyl mercaptan, is a chemical compound that serves as a reagent in organic synthesis. It is the sodium salt of methanethiol, a foul-smelling gas, and exhibits strong basic and nucleophilic properties. SODIUM METHANETHIOLATE is instrumental in the formation of carbon-sulfur bonds, making it a valuable asset in the synthesis of various organic compounds.

Uses

Used in Organic Synthesis:
Sodium methanethiolate is used as a reagent for the formation of carbon-sulfur bonds in organic synthesis. Its strong nucleophilic nature allows it to effectively participate in numerous chemical reactions, facilitating the creation of a wide range of organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, sodium methanethiolate is utilized in the production of specific drugs. Its role in creating carbon-sulfur bonds is crucial for the synthesis of certain medicinal compounds, contributing to the development of new and existing pharmaceuticals.
Used in Pesticide and Herbicide Manufacturing:
Sodium methanethiolate also finds application in the manufacturing of pesticides and herbicides. Its ability to form carbon-sulfur bonds is harnessed in the production of these agricultural chemicals, which are essential for controlling pests and unwanted plant growth.
It is important to handle sodium methanethiolate with care due to its corrosive nature, as it can cause burns upon contact with the skin. Proper safety measures should be taken to ensure the safe use of this chemical compound in various applications.

InChI:InChI=1/C9H10O2/c1-6-5-7-8(10)3-2-4-9(7)11-6/h5H,2-4H2,1H3

Upstream product

• 90534-81-9 4-(5'-methyl-2'-furyl)butanoic acid 
• 108-22-5 Isopropenyl acetate 
• 1460-08-8 2-diazocyclohexane-1,3-dione 
• 674-82-8 4-methyleneoxetan-2-one 
• 397251-91-1 2-(iodomethyl)-2,3,6,7-tetrahydrobenzofuran-4(5H)-one 
• 16868-65-8 2-(prop-2-yn-1-yl)cyclohexane-1,3-dione 
• 504-02-9 1,3-cylohexanedione 
• 123-38-6 propionaldehyde 
• 42738-68-1 2-allylcyclohexane-1,3-dione 
• 534-22-5 2-methylfuran 
• 620-02-0 5-Methylfurfural 
• 17162-95-7 3-(5-methyl-2-furanyl)-1-propanol 
• 82033-89-4 4-(5-methylfuran-2-yl)butanenitrile 
• 1456-08-2 3-(5'-methyl-2'-furyl)propanoic acid 

Downstream Products

• 36040-38-7 2-methyl-6-phenyl-4,5-dihydro-furo[2,3-c]acridine 
• 36040-41-2 2-methyl-6-phenyl-4,5-dihydro-benzo[a]furo[3,2-h]acridine 
• 1042149-14-3 2-methyl-3-(4-methoxyphenyl)-6,7-dihydro-5H-benzofuran-4-one 
• 1042149-12-1 2-methyl-3-(2-methoxyphenyl)-6,7-dihydro-5H-benzofuran-4-one 
• 1042149-13-2 2-methyl-3-(3-methoxyphenyl)-6,7-dihydro-5H-benzofuran-4-one 
• 1042149-07-4 2-methyl-3-phenyl-6,7-dihydro-5H-benzofuran-4-one 

Relevant articles and documents

Efficient synthesis of dihydrofurans and furans by rhodium(II)-catalyzed reactions of cyclic diazodicarbonyl compounds

An efficient synthesis of dihydrofurans and furans is achieved by rhodium-catalyzed reactions of cyclic diazodicarbonyl compounds with allyl halides. This method provides a rapid entry toward naturally occurring furocoumarin and furophenalenone derivative

Preparation of polysubstituted dihydrofurans through a PhI(OAc)2-promoted haloenolcyclization of olefinic dicarbonyl compounds

A metal-free cyclization of olefinic dicarbonyl compounds for the synthesis of various 5-halomethyl-4,5-dihydrofurans is presented. Using (diacetoxyiodo)benzene as the reaction promoter and halotrimethylsilane as the halogen source, the intramolecular hal

One-pot Synthesis of Dihydrofuran Derivatives by Ru Catalyzed Reaction

The present invention relates to a one-pot synthesis method of dihydrofuran derivatives using a ruthenium catalyst and, more particularly, to a one-pot synthesis method of dihydrofuran derivatives, which makes a reaction between cyclic/non-cyclic diazo dicarbonyl compound and olefin in the presence of ruthenium (II) phosphine complex as a reaction catalyst. The one-pot synthesis method of the present invention shortens time required for the reaction and improves synthesis yield. The diazo carbonyl compound represented by chemical formula 1, 2, or 3 reacts with olefin to form dihydrofuran derivatives through a [3+2] cyclization addition reaction.COPYRIGHT KIPO 2016

Synthesis and structure-activity relationships of a series of substituted 2-(1H-furo[2,3-g]indazol-1-yl)ethylamine derivatives as 5-HT2C receptor agonists

A series of novel indazole derivatives were synthesized, and their structure-activity relationships examined in order to identify potent and selective 5-HT2C receptor agonists. Among these compounds, (S)-2-(7-ethyl-1H-furo[2,3-g]indazol-1-yl)-1-methylethylamine (YM348) had a good in vitro profile, that is, high agonistic activity to the human 5-HT2C receptor subtype (EC50 = 1.0 nM) and high selectivity over 5-HT2A receptors. This compound was also effective in a rat penile erection model when administered po.