50629-82-8 Usage
Description
Halometasone, also known by its brand name SICORTEN, is a potent, topical steroid that belongs to the class of corticosteroids. It is effective in treating a variety of acute and chronic eczematous dermatoses and psoriasis. Notably, Halometasone is reported to be devoid of skin toxicity and systemic effects, making it a safe choice for treating skin disorders.
Uses
Used in Dermatology:
Halometasone is used as a topical steroid for the treatment of skin disorders such as chronic eczema and psoriasis. Its potent anti-inflammatory and immunosuppressive properties help alleviate symptoms and promote skin healing without causing significant side effects.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Halometasone is utilized as an active ingredient in various formulations, such as creams, ointments, and lotions, targeting skin conditions that require potent anti-inflammatory and immunosuppressive action. Its inclusion in these products helps improve the effectiveness of treatments for a range of dermatological issues.
Originator
Ciba-Geigy (Switzerland)
Check Digit Verification of cas no
The CAS Registry Mumber 50629-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,6,2 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50629-82:
(7*5)+(6*0)+(5*6)+(4*2)+(3*9)+(2*8)+(1*2)=118
118 % 10 = 8
So 50629-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C22H27ClF2O5/c1-10-4-11-12-5-15(24)13-6-16(27)14(23)7-19(13,2)21(12,25)17(28)8-20(11,3)22(10,30)18(29)9-26/h6-7,10-12,15,17,26,28,30H,4-5,8-9H2,1-3H3/t10-,11+,12+,15+,17+,19+,20+,21+,22+/m1/s1
50629-82-8Relevant articles and documents
Synthesis method and application of 9-fluorosteroid compound
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Paragraph 0089-0096; 0140-0142, (2021/01/15)
The invention provides a synthesis method and application of a 9-fluorosteroid compound, and relates to the technical field of chemical synthesis. The synthesis method of the 9-fluorosteroid compoundcomprises the following step: reacting a compound II in an ionic liquid containing hydrogen fluoride salt to obtain a 9-fluorosteroid compound III. According to the synthesis method of the 9-fluorosteroid compound, the ionic liquid containing the hydrogen fluoride salt is used as a fluorinating agent to replace a traditional hydrogen fluoride aqueous solution, volatilization of hydrogen fluoride gas is avoided, corrosivity is small, toxicity is greatly reduced, reaction conditions are mild, reaction can be completed at the room temperature, operability is high, the safety coefficient is high,and production applicability is improved. The synthesis method of the 9-fluorosteroid compound is used for preparing corticosteroid drugs, highly toxic chemical reagents are not used in the synthesisroute, the operability is high, the safety coefficient is high, and the production applicability is improved.