50637-83-7

Basic information

• Product Name: 6-bromo-2-(bromoacetyl)naphthalene
• Synonyms: 6-bromo-2-(bromoacetyl)naphthalene;2-bromo-1-(6-bromonaphthalen-2-yl)ethanone
• CAS NO: 50637-83-7
• Molecular Formula: C₁₂H₈Br₂O
• Molecular Weight: 327.99932
• EINECS: -0
• Mol File: 50637-83-7.mol
• Article Data: 22

Chemical Properties

• Melting Point: 112-113 °C
• Boiling Point: 400.6±20.0 °C(Predicted)
• Appearance: /
• Density: 1.778±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 6-bromo-2-(bromoacetyl)naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-2-(bromoacetyl)naphthalene(50637-83-7)
• EPA Substance Registry System: 6-bromo-2-(bromoacetyl)naphthalene(50637-83-7)

Safety Data

• Hazardous Substances Data: 50637-83-7(Hazardous Substances Data)

Upstream product

• 1590-25-6 1-(6-bromonaphthalen-2-yl)ethanone 
• 1256387-44-6 1-(6-bromo-naphthalen-2-yl)-2-diazo-ethanone 
• 861880-64-0 6-bromo-N-methoxy-N-methyl-2-naphthamide 
• 87700-60-5 6-bromonaphthalene-2-carbonyl chloride 
• 580-13-2 2-bromonaphthalene 
• 5773-80-8 6-bromo-2-naphthoic acid 
• 1303533-76-7 2,2-dibromo-1-(6-bromonaphthalen-2-yl)ethanone 
• 186581-53-3 diazomethane 
• 762-04-9 Diethyl phosphonate 

Downstream Products

• 50637-84-8 (3-Methylphenyl)-(6-brom-2-naphthacyl)-sulfid 
• 50637-82-6 (3-Brom-phenyl)-(6-brom-2-naphthacyl)-sulfid 
• 1315483-08-9 C₁₉H₁₃BrO₃ 
• 1303533-77-8 C₂₅H₂₂BrN₃O₂ 
• 1242087-97-3 C₄₁H₄₂N₆O₄ 
• 1303533-78-9 C₄₁H₄₂N₆O₄ 
• 1318898-49-5 1,1-dimethylethyl (2S,4S)-2-{4-[6-(3,4-diaminophenyl)-2-naphthalenyl]-1H-imidazol-2-yl}-4-methyl-1-pyrrolidinecarboxylate 
• 1318898-60-0 methyl {(1S)-1-[((2S,4S)-2-{5-[6-(2-{(2S,4S)-1-[(2R)-2-(dimethylamino)-2-phenylacetyl]-4-methyl-2-pyrrolidinyl}-1H-imidazol-4-yl)-2-naphthalenyl]-1H-benzimidazol-2-yl}-4-methyl-1-pyrrolidinyl)carbonyl]-2-methylpropyl}carbamate 
• 1318898-75-7 methyl ((1S)-2-methyl-1-{[(2S,3aS,6aS)-2-{5-[6-(2-{(2S,4S)-4-methyl-1-[(2R)-2-phenyl-2-(1-pyrrolidinyl)acetyl]-2-pyrrolidinyl}-1H-imidazol-4-yl)-2-naphthalenyl]-1H-benzimidazol-2-yl}hexahydrocyclopenta[b]pyrrol-1(2H)-yl]carbonyl}propyl)carbamate 

Relevant articles and documents

NOVEL BENZIMIDAZOLE DERIVATIVES

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS

A series of hepatitis C virus (HCV) inhibitors and compositions and applications thereof in the preparation of drugs for treating chronic HCV infection. Especially, a series of compounds that are used as NS5A inhibitors, and compositions and uses thereof in the preparations of drugs.

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.