50670-64-9 Usage
Description
5-Amino-2-methylbenzonitrile, also known as 2-methyl-5-aminobenzonitrile, is an organic compound with the molecular formula C8H8N2. It is a white crystalline solid that serves as an important intermediate in the synthesis of various organic compounds and pharmaceuticals. Its chemical structure features a benzene ring with a nitrile group at the 2nd position, an amino group at the 5th position, and a methyl group at the 2nd position as well.
Uses
Used in Pharmaceutical Industry:
5-Amino-2-methylbenzonitrile is used as a starting material for the synthesis of various pharmaceutical compounds. It plays a crucial role in the development of new drugs and the modification of existing ones to improve their efficacy and safety.
Used in Chemical Synthesis:
In the chemical industry, 5-Amino-2-methylbenzonitrile is used as a building block for the synthesis of a wide range of organic compounds, including dyes, pigments, and agrochemicals. Its versatile structure allows for various functional group transformations, making it a valuable component in the synthesis of complex molecules.
Used in the Synthesis of 5-Iodo-2-methylbenzonitrile:
5-Amino-2-methylbenzonitrile is used as a starting material for the synthesis of 5-iodo-2-methylbenzonitrile, which is an important intermediate in the production of pharmaceuticals and other organic compounds.
Used in the Synthesis of 5-Hydroxy-2-methylbenzonitrile:
It may also be used in the preparation of 5-hydroxy-2-methylbenzonitrile, another valuable intermediate in the synthesis of various organic compounds and pharmaceuticals.
Used in the Preparation of 5-(2,4-Dioxothiazolidin-3-yl)-2-methylbenzonitrile:
5-Amino-2-methylbenzonitrile can be reacted with thioglycolic acid methyl ester in the presence of 1,1′-carbonyldiimidazole to produce 5-(2,4-dioxothiazolidin-3-yl)-2-methylbenzonitrile, which has potential applications in the development of new pharmaceuticals and other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 50670-64-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,6,7 and 0 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 50670-64:
(7*5)+(6*0)+(5*6)+(4*7)+(3*0)+(2*6)+(1*4)=109
109 % 10 = 9
So 50670-64-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2/c1-6-2-3-8(10)4-7(6)5-9/h2-4H,10H2,1H3
50670-64-9Relevant articles and documents
Nickel Boride Catalyzed Reductions of Nitro Compounds and Azides: Nanocellulose-Supported Catalysts in Tandem Reactions
Proietti, Giampiero,Prathap, Kaniraj Jeya,Ye, Xinchen,Olsson, Richard T.,Dinér, Peter
, p. 133 - 146 (2021/11/04)
Nickel boride catalyst prepared in situ from NiCl2 and sodium borohydride allowed, in the presence of an aqueous solution of TEMPO-oxidized nanocellulose (0.01 wt%), the reduction of a wide range of nitroarenes and aliphatic nitro compounds. Here we describe how the modified nanocellulose has a stabilizing effect on the catalyst that enables low loading of the nickel salt pre-catalyst. Ni-B prepared in situ from a methanolic solution was also used to develop a greener and facile reduction of organic azides, offering a substantially lowered catalyst loading with respect to reported methods in the literature. Both aromatic and aliphatic azides were reduced, and the protocol is compatible with a one-pot Boc-protection of the obtained amine yielding the corresponding carbamates. Finally, bacterial crystalline nanocellulose was chosen as a support for the Ni-B catalyst to allow an easy recovery step of the catalyst and its recyclability for new reduction cycles.
Highly efficient triarylene conjugated dyes for sensitized solar cells
Chang, Yuan Jay,Chow, Tahsin J.
, p. 9523 - 9531 (2012/05/04)
A new series of organic dyes containing a triarylamine donor group, a triarylene-linked bridging moiety, and a cyanoacrylic acid acceptor group were synthesized through a simple procedure in high yields. A selected set of substituents were added onto the
SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP)
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Page/Page column 69, (2010/02/14)
The present invention discloses and claims a series of 2,3,5-substituted pyridone derivatives as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are inhibitors of poly(adenosine 5'-diphosphate ribose) polymerase (PARP) and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases, including diseases associated with the central nervous system and cardiovascular disorders.
