50678-83-6Relevant articles and documents
Room Temperature Metal-Catalyzed Oxidative Acylation of Electron-Deficient Heteroarenes with Alkynes, Its Mechanism, and Application Studies
Sharma, Shweta,Kumar, Mukesh,Vishwakarma, Ram A.,Verma, Mahendra K.,Singh, Parvinder Pal
, p. 12420 - 12431 (2018)
Herein, we report an original one-step, simple, room-temperature, regioselective Minisci reaction for the acylation of electron-deficient heteroarenes with alkynes. The method has broad functional group compatibility and gives exclusively monoacylated products in good to excellent yields. The mechanistic pathway was analyzed based on a series of experiments confirming the involvement of a radical pathway. The 18O-labeling experiment suggested that water is a source of oxygen in the acylated product, and head space GC-MS experiment shows the C-C cleavage occurs via release as CO2.
Pyrolysis of 2 (2 azidobenzoyl)pyridine and 3 (2 pyridyl) 2,1 benzisoxazoles. Preparation and chemistry of some pyrido[1,2 b]cinnolin 6 ium hydroxide inner salts
Ning,Chen,Sternbach
, p. 125 - 134 (2007/10/04)
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