5068-21-3Relevant articles and documents
Ultrashort Hδ+?Hδ?intermolecular distance in a supramolecular system in the solid state
Frontera, Antonio,García-Márquez, Alfonso,Gramage-Doria, Rafael,Roisnel, Thierry
, p. 7112 - 7115 (2021/07/28)
Herein we report experimental evidence for the shortest intermolecular distance reported for two electronically-different hydrogen atoms in the solid state. The Hδ+?Hδ?non-covalent interaction was studied using theoretical calculatio
Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives
Fujii, Shinya,Hashimoto, Yuichi,Matsumoto, Yuichiro,Saito, Hiroki
, (2020/01/28)
Increasing structural options in medicinal chemistry is important for the development of novel and distinctive drug candidates. In this study, we focused on phosphorus-containing functionalities. We designed and synthesized a series of phosphinophenol der
Preparation method of amphiphilic PN = PS type phosphorus-containing crown macromolecular nano-micelle and application of crown macromolecular nano-micelle as drug carrier
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Paragraph 0076; 0083, (2020/11/10)
The invention relates to a preparation method of amphipathic PN = PS type phosphorus-containing crown macromolecule nano-micelle and application of the crown macromolecular nano-micelle as a drug carrier. The obtained amphipathic phosphorus-containing crown macromolecule can be self-assembled into the nano-micelle in water, and a hydrophobic drug can be embedded into a hydrophobic cavity in the nano-micelle to form a stable compound. The method disclosed by the invention is simple, high in reaction controllability, easy in operation and separation, low in cost, uniform in final product molecular weight and commercialized in raw material source, and has a good development prospect.