50694-31-0Relevant articles and documents
Synthesis and reactivity of functional 1-methyl-silacyclopentenes
Heinicke, J.,Gehrhus, B.,Meinel, S.
, p. 71 - 82 (1994)
The silylenes MeSiCl, MeSiOMe and MeSiNMe2 can be thermally generated from disilanes and trapped by butadiene, isoprene and 2,3-dimethylbutadiene to give functionally-substituted silacyclopentenes.Some examples of cycloadditions to heterodienes are includ
Enantioselective Synthesis of Silacyclopentanes
Igawa, Kazunobu,Yoshihiro, Daisuke,Abe, Yusuke,Tomooka, Katsuhiko
, p. 5814 - 5818 (2016/05/09)
A variety of functionalized silacyclopentanes were synthesized by highly enantioselective β-eliminations of silacyclopentene oxides followed by stereospecific transformations. The reaction mechanism of the β-elimination was elucidated by DFT calculations. An in vitro biological assay with an oxy-functionalized silacyclopentane showed substantial binding to a serotonin receptor protein.
DIORGANOSILACYCLOPENT-3-ENE DERIVATIVES FROM DIORGANODICHLOROSILANES AND BUTADIENEMAGNESIUM: EVIDENCE FOR CROTYL-GRIGNARD INTERMEDIATES
Richter, Wolf Juergen
, p. 45 - 50 (2007/10/02)
Reactions of substituted dichlorosilanes, R1R2SiCl2 (R1=CH3, R2=Ph, vinyl), with butadienemagnesium yield methoxybutenylsilane derivatives and silacyclopent-3-enes after treatment with methanol at -70 deg C.For R=vinyl, a substituted cyclodeca-3,8-diene is formed in addition to the 1,4-disilylated butenylic species.The nature of the range of products suggests that silyl-substituted crotyl-Grignard compounds are the major intermediates.
