50735-55-2

Basic information

• Product Name: 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE
• Synonyms: 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE
• CAS NO: 50735-55-2
• Molecular Formula: C₁₃H₁₁BrN₂O
• Molecular Weight: 291.14
• Mol File: 50735-55-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 352.8°C at 760 mmHg
• Flash Point: 167.2°C
• Appearance: /
• Density: 1.558g/cm³
• Vapor Pressure: 3.74E-05mmHg at 25°C
• Refractive Index: 1.707
• CAS DataBase Reference: 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE(50735-55-2)
• EPA Substance Registry System: 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE(50735-55-2)

Safety Data

• Hazardous Substances Data: 50735-55-2(Hazardous Substances Data)

Usage

General Description

2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE, also known as 4-Bromo-2-aminobenzamide, is a chemical compound with the molecular formula C13H10BrN3O. It is a derivative of benzamide with a bromine substituent attached to the phenyl ring. 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE is commonly used in organic synthesis and medicinal chemistry research. It has been studied for its potential use as a building block in the development of pharmaceuticals and as a tool in the investigation of biological processes. The chemical structure and properties of 2-AMINO-N-(4-BROMOPHENYL)BENZAMIDE make it a valuable tool for the development of new chemical compounds and understanding the mechanisms of action in biological systems.

InChI:InChI=1/C13H11BrN2O/c14-9-5-7-10(8-6-9)16-13(17)11-3-1-2-4-12(11)15/h1-8H,15H2,(H,16,17)

Upstream product

• 118-48-9 isatoic anhydride 
• 106-40-1 4-bromo-aniline 
• 118-92-3 anthranilic acid 
• 2385-26-4 N-(4-bromophenyl)-2-nitrobenzamide 
• 91-56-5 indole-2,3-dione 
• 610-14-0 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 21563-73-5 2-aminobenzoyl chloride 

Downstream Products

• 2401-10-7 3-(4'-Bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 24122-32-5 3-(4-bromophenyl)-4(3H)-quinazolinone 
• 94565-44-3 3-(4-Bromo-phenyl)-2-((E)-styryl)-2,3-dihydro-1H-quinazolin-4-one 
• 84770-65-0 2-Phenyl-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 94565-56-7 3-(4-Bromo-phenyl)-2-(4-hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one 
• 94565-34-1 3-(4-Bromo-phenyl)-2-(4-hydroxy-3-methoxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one 
• 94565-39-6 3-(4-Bromo-phenyl)-2-(3,4-dimethoxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one 
• 84770-66-1 2,2-Dimethyl-3-(4'-bromophenyl)-1,2,3,4-tetrahydroquinazolin-4-one 
• 84770-67-2 3-(4-Bromo-phenyl)-2-ethyl-2-methyl-2,3-dihydro-1H-quinazolin-4-one 
• 256430-26-9 4'-Bromo-2-[(ethoxycarbonyl)amino]benzanilide 
• 101440-64-6 3-(4-bromo-phenyl)-2-propyl-3H-quinazolin-4-one 
• 25628-97-1 3-(4-bromo-phenyl)-2-ethyl-3H-quinazolin-4-one 
• 951760-09-1 2-amino-N-(4-bromophenyl)benzylamine 
• 2400-96-6 3-(p-Bromphenyl)-2,4-dioxotetrahydrochinazolin 

Relevant articles and documents

N,N-Dimethylformamide as Carbon Synthons for the Synthesis ofN-Heterocycles: Pyrrolo/Indolo[1,2-a]quinoxalines and Quinazolin-4-ones

N,N-dimethylformamide (DMF) as synthetic precursors contributing especially the methyl, acyl, and amino groups has played a significant role in heterocycle syntheses and functionalization. In this protocol, a wide range of pyrrolo/indolo[1,2-a]quinoxalines and quinazolin-4-ones were obtained in moderate to good yields by using elemental iodine without any metal or peroxides. We considered thatN-methyl andN-acyl of DMF participate and complete the reaction separately through different mechanisms, which displayed potential still to be explored of DMF.

Synthesis and biological evaluation of novel benodanil-heterocyclic carboxamide hybrids as a potential succinate dehydrogenase inhibitors

In order to discover new antifungal agents, twenty novel benodanil-heterocyclic carboxamide hybrids were designed, synthesized, and characterized by 1H NMR and HRMS. In vitro, their antifungal activities against four phytopathogenic fungi were

Sustainable methine sources for the synthesis of heterocycles under metal- and peroxide-free conditions

Alcohols and ethers were identified as sustainable methine sources for synthesizing quinazolinone and benzimidazole derivatives using a combination of TsOH·H2O/O2 and appropriate bis-nucleophiles for the first time. Deuterium labeling studies clearly proved that the C2 hydrogen of the synthesized heterocycles came from the methine source. These unique reaction conditions were successfully applied to the synthesis of echinozolinone (2e′), 2f′ (a common precursor of rutaecarpine and (±) evodiamine), and dimedazole (6d). Notable features of this method include its low toxicity, use of commercial feedstocks as substrates, low cost, broad functional group tolerance and suitability for a wide range of bis-nucleophilic starting materials.