50735-58-5Relevant articles and documents
Stereoselective Synthesis of cis-2,5-Disubstituted Pyrrolidines via Copper-Catalyzed Cyclization of Alkenes
Cai, Sai-Hu,Da, Bing-Chao,Zhou, Jia-Hui,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 1076 - 1080 (2016/11/25)
An efficient methodology for the stereoselective synthesis of cis-2,5-disubstituted pyrrolidines using copper catalyst was developed. The corresponding cis-2,5-disubstituted pyrrolidines could be obtained in reasonable yields and with good stereoselectivities in the presence of 4,4′-di-tert-butyl-2,2′-bipyridine as ligand and 1-methyl-2-pyrrolidinone as solvent.