50742-63-7Relevant articles and documents
DOPAMINE D2 RECEPTOR LIGANDS
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Page/Page column 239, (2016/07/05)
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity. The present invention relates to novel compounds that modulate dopamine D2 receptors. In particular, compounds of the present invention show functional selectivity at the dopamine D2 receptors and exhibit selectivity downstream of the D2 receptors, on the 0- arrestin pathway and/or on the cAMP pathway.
Base Catalysed Rearrangements Involving Ylide Intermediates. Part 12. The Preparation and Reactions of 2-Oxidoanilinium Ylides
Ollis, W. David,Sutherland, Ian O.,Thebtaranonth, Yodhathai
, p. 1981 - 1993 (2007/10/02)
2-Oxidoanilinium ylides (22) may be prepared from the corresponding quarternary salts (21) by reaction with aqueous sodium hydroxide.The ylides (22) rearrange on heating to give the products (23) of rearrangements which, on the basis of mixing exper