507476-70-2Relevant articles and documents
NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF
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Paragraph 0042, (2019/06/17)
The present invention relates to photoactivatable compounds and methods of use thereof for determining binding site and other structural information about RNA transcripts. The invention also provides methods of identifying RNA transcripts that bind compounds and are thus druggable, methods of screening drug candidates, and methods of determining drug binding sites and/or accessible or reactive sites on a target RNA.
POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS
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Paragraph 00229; 00231, (2017/07/06)
The present invention relates to compounds of Formula (I) and pharmaceutically acceptable compositions thereof, useful as toll-like receptor 7/8 (TLR7/8) antagonists. In Formula (I), Ring A is aryl or heteroaryl; Ring B is aryl or heteroary; and X is C(R4)2, O, NR4, S, S(R4), or S(R4)2.
CCR6 COMPOUNDS
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Paragraph 0114, (2015/06/18)
Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6. Pharmaceutical compositions of the compounds of formula (I) are also provided. Further provided in the present disclosure