507485-39-4

Basic information

• Product Name: 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione
• Synonyms: 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione
• CAS NO: 507485-39-4
• Molecular Weight: 348.404
• Mol File: 507485-39-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione(507485-39-4)
• EPA Substance Registry System: 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione(507485-39-4)

Safety Data

• Hazardous Substances Data: 507485-39-4(Hazardous Substances Data)

Upstream product

• 316148-58-0 ethyl 5-(1,1-dimethyl-2-propenyl)imidazole-4-carboxylate 
• 316148-59-1 (5-(1,1-dimethyl-2-propenyl)imidazole-4-yl)methanol 
• 316148-57-9 ethyl 2-chloro-3-oxo-4,4-dimethyl-5-hexenoate 
• 316148-60-4 5-(1,1-dimethyl-2-propenyl)imidazole-4-carbaldehyde 
• 69737-23-1 methyl 3-hydroxy-2,2-dimethylbutanoate 
• 66248-79-1 ethyl 4,4-dimethyl-3-oxo-hex-5-enoate 
• 19757-86-9 methyl 2,2-dimethyl-3-pentenoate 
• 57690-96-7 2,2-dimethylbut-3-enoyl chloride 
• 10276-09-2 2,2-dimethyl-but-3-enoic acid 
• 714273-85-5 2,2-dimethyl-3-(toluene-4-sulfonyloxy)-butyric acid methyl ester 
• 714273-82-2 1-acetyl-3-{(Z)-1-[5-(1,1-dimethyl-2-propenyl)-1H-4-imidazolyl]methylidene}-2,5-piperazinedione 
• 100-52-7 benzaldehyde 
• 351325-37-6 3Z-benzylidene-6Z-[[5-(1,1-dimethyl-2-propenyl)-1H-imidazol-4-yl]methylene]-2,5-piperazinedione 

Downstream Products

• 351325-37-6 3Z-benzylidene-6Z-[[5-(1,1-dimethyl-2-propenyl)-1H-imidazol-4-yl]methylene]-2,5-piperazinedione 

Relevant articles and documents

A novel potent cell cycle inhibitor dehydrophenylahistin. - Enzymatic synthesis and inhibitory activity toward sea urchin embryo

A novel dehydrogenated cyclic dipeptide named as dehydrophenylahistin (APLH) was effectively prepared from a fungal metabolite (-)-phenylahistin by the enzymatic conversion catalyzed by the cell-free extract of Streptomyces albulus KO-23, an albonoursin-producing actinomycete. ΔPLH exhibited more than 1,000 times as high potent inhibitory activity toward the first cleavage of sea urchin embryos as (-)-phenylahisitn which has been reported to be a cell cycle inhibitor and more than 10,000 as high as albonoursin, indicating that ΔPLH is a promising leading compound for anticancer drugs.