50787-09-2 Usage
Description
2-Acetamido-2-deoxy-3-O-(beta-D-galactopyranosyl)-D-glucopyranose, also known as Galb1?3GlcNAc, is a complex carbohydrate molecule that serves as a crucial component in the structure of various antigenic determinants. It is derived from blood group A, B, H, and Lewis compounds and is characterized by its white crystalline solid appearance. This molecule plays a significant role in the biological processes and interactions within the human body, particularly in the context of blood group antigens and the immune system.
Uses
Used in Biochemical Research:
2-Acetamido-2-deoxy-3-O-(beta-D-galactopyranosyl)-D-glucopyranose is used as a substrate for the alpha1,2-fucosyltransferase enzyme from Helicobacter pylori. This application is essential for studying the enzyme's function and its role in the pathogenesis of H. pylori infections.
Used in Immunology and Blood Group Typing:
In the field of immunology, 2-Acetamido-2-deoxy-3-O-(beta-D-galactopyranosyl)-D-glucopyranose is used as a component of antigenic determinants, which are crucial for the identification and classification of blood groups. This molecule helps in understanding the genetic basis of blood group variations and plays a vital role in the development of diagnostic tools and techniques for blood typing.
Used in Pharmaceutical Industry:
The molecule is also used in the pharmaceutical industry for the development of drugs targeting specific antigenic determinants. By understanding the structure and function of Galb1?3GlcNAc, researchers can design drugs that can selectively target these determinants, potentially leading to more effective treatments for various diseases and conditions.
Used in Glycobiology and Glycochemistry:
In the fields of glycobiology and glycochemistry, 2-Acetamido-2-deoxy-3-O-(beta-D-galactopyranosyl)-D-glucopyranose is used as a model compound to study the structure, function, and interactions of complex carbohydrates. This research contributes to the broader understanding of glycans and their role in biological processes, which can have implications for the development of new therapeutic strategies and diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 50787-09-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,7,8 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 50787-09:
(7*5)+(6*0)+(5*7)+(4*8)+(3*7)+(2*0)+(1*9)=132
132 % 10 = 2
So 50787-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H25NO11/c1-4(18)15-7-12(9(20)6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13?,14+/m1/s1
50787-09-2Relevant articles and documents
Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk
Nishimoto, Mamoru,Kitaoka, Motomitsu
, p. 2101 - 2104 (2008/02/13)
A one-pot enzymatic reaction to produce lacto-N-biose I (LNB), which is supposed to represent the bifidus factor in human milk oligosaccharides, was demonstrated. Approximately 500mM of LNB was generated in 10-liter of reaction mixture initially containing 660 mM of sucrose and 600mM of GlcNAc by the concurrent actions of four enzymes, sucrose phosphorylase, UDP-glucose - hexose-1-phospate uridylyltransferase, UDP-glucose 4-epimerase, and lacto-N-biose phosphorylase, in the presence of UDP-Glc and phosphate, indicating a reaction yield of 83%. LNB was isolated from the mixture by crystallization after yeast treatment. Finally, 1.4 kg of LNB of 99.6% purity was recovered after recrystallization.
