50800-39-0Relevant articles and documents
Rate Enhancement in CAN-Promoted Pd(PPh3)2Cl2-Catalyzed Oxidative Cyclization: Synthesis of 2-Ketofuran-4-carboxylate Esters
Ruengsangtongkul, Sureeporn,Chaisan, Nattawadee,Thongsornkleeb, Charnsak,Tummatorn, Jumreang,Ruchirawat, Somsak
supporting information, p. 2514 - 2517 (2019/04/30)
Stoichiometric ceric ammonium nitrate (CAN) and a catalytic amount of Pd(PPh3)2Cl2 (5 mol %) can rapidly produce multisubstituted 2-ketofuran-4-carboxylate esters from 2-propargylic 1,3-ketoesters via oxidative O-cyclization reaction. Pd(PPh3)2Cl2 was found to be the crucial catalyst as its inclusion greatly enhanced the rate of the reaction and cleanly afforded the products within minutes. Over 30 substrates were successfully converted to the desired compounds in mostly moderate to good yields.
PIFA-mediated oxidative cycloisomerization of 2-propargyl-1,3-dicarbonyl compounds: Divergent synthesis of furfuryl alcohols and furfurals
Saito, Akio,Anzai, Toshiyuki,Matsumoto, Asami,Hanzawa, Yuji
experimental part, p. 4658 - 4661 (2011/09/30)
PhI(OCOCF3)2 (PIFA) in the presence of trifluoroacetic acid (TFA) in CH2Cl2 efficiently promotes the oxidative cycloisomerization of 2-propargyl 1,3-dicarbonyl compounds to give 4,5-disubstituted furfuryl alcoho
Iron-catalyzed domino process for the synthesis of α-carbonyl furan derivatives via one-pot cyclization reaction
Jiang, Huanfeng,Yao, Wenjuan,Cao, Hua,Huang, Huawen,Cao, Derong
experimental part, p. 5347 - 5350 (2010/10/20)
(Figure presented) The Fe(ClO4)3-catalyzed intramolecular rearrangement/cyclization/oxidation reaction sequence for the synthesis of α-carbonyl furan derivatives from electron-deficient alkynes and 2-yn-1-ols is reported.
