50817-48-6

Basic information

• Product Name: Benzoic acid, 4-methyl-2-[(1-methylethyl)amino]-
• CAS NO: 50817-48-6
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Mol File: 50817-48-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-methyl-2-[(1-methylethyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-methyl-2-[(1-methylethyl)amino]-(50817-48-6)
• EPA Substance Registry System: Benzoic acid, 4-methyl-2-[(1-methylethyl)amino]-(50817-48-6)

Safety Data

• Hazardous Substances Data: 50817-48-6(Hazardous Substances Data)

Upstream product

• 75-31-0 isopropylamine 
• 7697-27-0 2-bromo-4-methylbenzoic acid 

Relevant articles and documents

Studies on 4(1H)-quinazolinones. 5. Synthesis and antiinflammatory activity of 4(1H)-quinazolinone derivatives

A number of new 4(1H)-quinazolinones were synthesized and evaluated in the carrageenin-induced paw edema test. Most of the compounds were obtained by the cyclization of the appropriately substituted anthranilamides with acid chlorides, followed by further chemical transformation. Structure-activity data suggest that 2-isopropyl-1-phenyl-, 2-cyclopropyl-1-phenyl-, and 1-isopropyl-2-phenyl-4(1H)-quinazolinones afford optimal potency and the presence of a halogen atom is preferred for activity. Adrenalectomy does not affect the antiinflammatory test results. The best result taking into account both efficacy and side effects was displayed by 1-isoproyl-(2-fluorophenyl)-4(1H)-quinazolinone.