50837-35-9

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 5-(acetyloxy)-2-(3,4-dimethoxyphenyl)-3,7-dimethoxy-
• CAS NO: 50837-35-9
• Molecular Formula: C21H20O8
• Molecular Weight: 400.385
• Mol File: 50837-35-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 5-(acetyloxy)-2-(3,4-dimethoxyphenyl)-3,7-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 5-(acetyloxy)-2-(3,4-dimethoxyphenyl)-3,7-dimethoxy-(50837-35-9)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 5-(acetyloxy)-2-(3,4-dimethoxyphenyl)-3,7-dimethoxy-(50837-35-9)

Safety Data

• Hazardous Substances Data: 50837-35-9(Hazardous Substances Data)

Upstream product

• 1245-15-4 retusin 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Antiproliferative activities of citrus flavonoids against six human cancer cell lines

Citrus fruits contain high concentrations of several classes of phenols, including numerous hydroxycinnamates, flavonoid glycosides, and polymethoxylated flavones. The latter group of compounds occurs without glycosidic linkages and has been shown to inhibit the proliferation of a number of cancer cell lines. This antiproliferative property was further demonstrated against additional human cancer cell lines, and the antiproliferative actions of a series of synthetic methoxylated flavones were also studied. Similar to the naturally occurring compounds, the synthetic compounds exhibited strong antiproliferative activities. In many cases the IC50 values occurred below 10 μm. Other hydroxylated flavone and flavanone aglycons also exhibited antiproliferative activities against the cancer cell lines, with the flavones showing greater activities than the flavanones. Glycosylation of these compounds removed their activity. The strong antiproliferative activities of the polymethoxylated flavones suggest that they may have use as anticancer agents in humans.

Chemical study of the cactus Ariocarpus retusus.

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