50839-66-2

Basic information

• Product Name: 1-(2-Hydroxyethyl)-2,3,3-trimethyl-3H-indolium iodide
• Synonyms: 1-(2-Hydroxyethyl)-2,3,3-trimethyl-3H-indolium iodide;2-(2,3,3-trimethylindol-1-ium-1-yl)ethanol,iodide
• CAS NO: 50839-66-2
• Molecular Formula: C₁₃H₁₈NO*I
• Molecular Weight: 331.19
• Mol File: 50839-66-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 168-169°C
• Appearance: /
• CAS DataBase Reference: 1-(2-Hydroxyethyl)-2,3,3-trimethyl-3H-indolium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Hydroxyethyl)-2,3,3-trimethyl-3H-indolium iodide(50839-66-2)
• EPA Substance Registry System: 1-(2-Hydroxyethyl)-2,3,3-trimethyl-3H-indolium iodide(50839-66-2)

Safety Data

• Hazardous Substances Data: 50839-66-2(Hazardous Substances Data)

Usage

General Description

1-(2-Hydroxyethyl)-2,3,3-trimethyl-3H-indolium iodide, also known as WST-1, is a water-soluble, redox-sensitive dye commonly used in cell proliferation and cytotoxicity assays. It is a stable, non-toxic salt that can be easily dissolved in aqueous solutions, making it suitable for use in cell culture media and biological buffers. WST-1 is often utilized in the measurement of cell viability and metabolic activity, as it undergoes a colorimetric change when reduced by cellular dehydrogenases. This change in color can be quantitatively measured to assess the number and/or activity of viable cells in a given sample, providing valuable information for a wide range of research and clinical applications.

InChI:InChI=1/C13H18NO.HI/c1-10-13(2,3)11-6-4-5-7-12(11)14(10)8-9-15;/h4-7,15H,8-9H2,1-3H3;1H/q+1;/p-1

Upstream product

• 624-76-0 Iodoethanol 
• 1640-39-7 2,3,3-trimethylindoleniune 

Downstream Products

• 51031-55-1 2-[trans-2-(9,9-dimethyl-2,3-dihydro-9H-oxazolo[3,2-a]indol-9a-yl)-vinyl]-6-nitro-phenol 
• 50839-68-4 2-methyl-acrylic acid 2-[trans-2-(9,9-dimethyl-2,3-dihydro-9H-oxazolo[3,2-a]indol-9a-yl)-vinyl]-6-nitro-phenyl ester 

Relevant articles and documents

Elaboration of multimodal ligands based on BOX units: Toward full zinc release in Zn(II) complexes by external stimulation

The development of molecular switches such as photochromic and electrochromic systems still represents a major concern in numerous application fields. If numerous pure organic switch families have been explored so far, concerning the coordination compounds, the choice seems more limited. In this context, we are exploring the possibility to elaborate a new addressable ligand family based on benzazolo-oxazolidine (BOX) moiety, a poorly investigated switch family, known for its acido-, electro- and photochromism properties. As proof of concept, two ligands bearing a BOX moiety were prepared using a pyridine as metal binding site after what corresponding Zn(II) complexes were synthesized and characterized. The acido-, electro- and photochemical behaviors of the free ligand as well as complexes were studied. This study reveals a subtle and interesting tautomeric equilibrium between oxazolidine ring opening and pyridine protonation whatever the nature of the stimulation. More interestingly, it conducts to observe the possibility to catch and release zinc ion on demand by using two external and orthogonal stimulations.

PEGylated cyanine dye nanoparticles as photothermal agents for mosquito and cancer cell control

Conversion of light energy to heat via photothermal conversion agents (PTCAs) is of great interest and has potential applications. Here, we described a heptamethine cyanine (Cy7) dye nanoparticles (Cy7-PEG NPs) prepared from heptamethine cyanine and poly(

Synthesis, structural and nonlinear optical properties of 2-(3-Cyano-4-{5-[1-(2-Hydroxyethyl)-3,3-dimethyl-1,3-dihydro-indol-2-ylidene] -Penta-1,3-dienyl}-5,5-dimethyl-5H-furan-2-ylidene)-malononitrile

A chromophore for nonlinear optics with extended conjugation has been synthesized, and its structure determined from X-ray diffraction data. The compound crystallizes in the monoclinic system with the space group P2 1/n and Z = 4. The unit cell parameters are a = 10.7826(4) A, b = 14.5943(5) A, c = 15.3792(5) and beta = 96.213(2). A thin film containing 5% of the chromophore in amorphous polycarbonate when poled at 180C and 60 V/m yields a maximum r33 value of 206 pm/V. This is seven times higher than the value found for the archetypical inorganic material, lithium niobate. Copyright Taylor &Francis Group, LLC.

Preparation method of novel dispiropyran chromophore

The invention discloses a preparation method of novel dispiropyran chromophore. Salicylaldehyde and trioxymethylene are used as raw materials, glacial acetic acid is used as a solvent, thick sulfuricacid is used as a catalyst to synthesize a salicylaldehy