50846-93-0

Basic information

• Product Name: Ethanone, 2-chloro-1-(2-naphthalenyl)- (9CI)
• Synonyms: Ethanone, 2-chloro-1-(2-naphthalenyl)- (9CI);2-(2-Chloroacetyl)naphthalene
• CAS NO: 50846-93-0
• Molecular Formula: C₁₂H₉ClO
• Molecular Weight: 204.65226
• Product Categories: ACETYLHALIDE
• Mol File: 50846-93-0.mol
• Article Data: 18

Chemical Properties

• Melting Point: 30 °C
• Boiling Point: 185-187 °C(Press: 10 Torr)
• Appearance: /
• Density: 1.229±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethanone, 2-chloro-1-(2-naphthalenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-(2-naphthalenyl)- (9CI)(50846-93-0)
• EPA Substance Registry System: Ethanone, 2-chloro-1-(2-naphthalenyl)- (9CI)(50846-93-0)

Safety Data

• Hazardous Substances Data: 50846-93-0(Hazardous Substances Data)

Upstream product

• 91-20-3 naphthalene 
• 79-04-9 chloroacetyl chloride 
• 93-08-3 methyl 2-naphthyl ketone 
• 162147-96-8 2-chloro-1-(2-naphthyl)-2-(phenylsulfinyl)-1-ethanone 
• 613-54-7 2-Bromo-2'-acetonaphthone 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 24197-66-8 S-chloroacetyl-p-mercaptotoluene 
• 32316-92-0 naphthalene-2-boronic acid 
• 186581-53-3 diazomethane 
• 2243-83-6 2-naphthaloyl chloride 
• 2459-25-8 methyl naphthalene-2-carboxylate 
• 1643-19-2 tetrabutylammomium bromide 
• 1292766-17-6 copper(I) thiophene-2-carboxylate 

Downstream Products

• 93-09-4 naphthalene-2-carboxylate 
• 133549-86-7 6-Cyclohexyl-4-(2-naphthalen-2-yl-2-oxo-ethyl)-2-phenyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione 
• 782-28-5 4-(2-naphthyl)butyric acid 
• 1590-22-3 4-(2-naphthyl)-4-oxobutyric acid 
• 93-08-3 methyl 2-naphthyl ketone 

Relevant articles and documents

A practical synthesis of α-bromo/iodo/chloroketones from olefins under visible-light irradiation conditions

A practical synthesis of α-bromo/iodo/chloroketones from olefins under visible-light irradiation conditions has been developed. In the presence of PhI(OAc)2 as promoter and under ambient conditions, the reactions of styrenes and triiodomethane undergo the transformation smoothly to deliver the corresponding α-iodoketones without additional photocatalyst in good yields under sunlight irradiation. Meanwhile, the reactions of styrenes with tribromomethane and trichloromethane generate the desired α-bromoketones and α-chloroketones in high yields by using Ru(bpy)3Cl2 as a photocatalyst under blue LED (450–455 nm) irradiation.

Iridium-Catalyzed Asymmetric Hydrogenation of Halogenated Ketones for the Efficient Construction of Chiral Halohydrins

Iridium-catalyzed asymmetric hydrogenation of prochiral halogenated ketones was successfully developed to prepare various chiral halohydrins with high reactivities and excellent enantioselectivities under basic reaction condition (up to >99% conversion, 99% yield, >99% ee). Moreover, gram-scale experiment was performed well in the presence of just 0.005 mol% (S/C=20 000) Ir/f-amphox catalyst with 99% yield and >99% ee. (Figure presented.).

Target-oriented synthesis: Miscellaneous synthetic routes to access 1,4-enediones through the coupling of 1,3-dicarbonyl compounds with multiform substrates

Target-oriented synthetic protocol was presented for the synthesis of 1,4-enediones. The approach can efficiently construct 1,4-enediones through different reaction pathways from multiform substrates α-halo aromatic ketones, 2-hydroxy-aromatic ketones and methyl carbinols. In this reaction, CuI was found to be the most efficient catalyst. Multiform substrates were also found to perform well to afford the products in a one-pot fashion.