50868-75-2

Basic information

• Product Name: N-(5-methoxy-2-methyl-phenyl)acetamide
• Synonyms: N-(5-methoxy-2-methyl-phenyl)acetamide
• CAS NO: 50868-75-2
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Mol File: 50868-75-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 327.9°Cat760mmHg
• Flash Point: 152.1°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 0.000196mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: N-(5-methoxy-2-methyl-phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-methoxy-2-methyl-phenyl)acetamide(50868-75-2)
• EPA Substance Registry System: N-(5-methoxy-2-methyl-phenyl)acetamide(50868-75-2)

Safety Data

• Hazardous Substances Data: 50868-75-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13NO2/c1-7-4-5-9(13-3)6-10(7)11-8(2)12/h4-6H,1-3H3,(H,11,12)

Upstream product

• 108-24-7 acetic anhydride 
• 50868-72-9 5-methoxy-o-toluidine 
• 77-78-1 dimethyl sulfate 
• 17484-36-5 4-Methyl-3-nitroanisole 
• 75-36-5 acetyl chloride 
• 112359-25-8 5-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate 
• 588-16-9 m-methoxyacetanilide 
• 536-90-3 m-Anisidine 

Downstream Products

• 871878-59-0 acetic acid-(4-bromo-5-methoxy-2-methyl-anilide) 
• 361162-90-5 5-methoxy-2-methyl-4-nitroacetanilide 
• 50868-78-5 2-acetamido-4-methoxybenzoic acid 
• 84575-26-8 2-amino-4-methoxybenzoic acid hydrochloride 
• 197156-25-5 5-methoxy-2-methylphenyl-3'-methoxyphenylamine 
• 197156-27-7 1,6-Dimethoxy-4-methyl-acridine-9-carboxylic acid 2,3,6-trifluoro-phenyl ester 
• 197156-28-8 1,6-Dimethoxy-4-methyl-9,10-dihydro-acridine-9-carboxylic acid 2,3,6-trifluoro-phenyl ester 
• 35214-95-0 2,3-Dihydro-5-hydroxypyrrolo<2,1-b>chinazolin-9(1H)-on 
• 106579-00-4 5-methoxy-2-methyl-4-nitroaniline 
• 99-21-8 2-methoxy-4-benzoylamino-5-methyl-aniline 
• 859944-07-3 benzoic acid-(5-methoxy-2-methyl-4-nitro-anilide) 
• 861546-94-3 2-(carboxymethyl-amino)-4-methoxy-benzoic acid 
• 4294-95-5 4-methoxyanthranilic acid 
• 152626-77-2 4-bromo-5-methoxy-2-methylaniline 

Relevant articles and documents

Synthesis of indenoquinolinone through aryne-mediated Pd(II)-catalysed remote C–H activation

Abstract: [Figure not available: see fulltext.]Indenoquinolinones have been synthesized from 2-haloquinoline-3-carbaldehyde through Pd-mediated simultaneous C–H (aldehyde) and C–X bond activation. DFT studies were performed to investigate the mechanistic pathway, and in situ UV–Vis studies indicate the presence of Pd(II) intermediate species. Aryne ligated Pd complex is actual intermediate in these reactions. Ligation of reactive aryne to Pd reduces probability of side reactions. Graphic abstract: [Figure not available: see fulltext.]

PISTON FOR AN INTERNAL COMBUSTION ENGINE AND METHOD FOR PRODUCING THE PISTON FOR AN INTERNAL COMBUSTION ENGINE

The present invention relates to compounds of general formula (I), wherein A represents an optionally substituted heterocycle group, B represents an aryl or heteroaryl group and wherein X, R1, R2, R3, R4 and R5 are as defined in the description. Compounds of formula (I) are useful to destroy, inhibit, or prevent the growth or spread of cells, especially malignant cells, into surrounding tissues implicated in a variety of human and animal diseases.

SULFONAMIDE COMPOUNDS USEFUL AS CYP17 INHIBITORS

Disclosed are sulfonamide compounds of Formula (I): or stereoisomers, N-oxides, prodrugs, or pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, R4 and R5 are defined herein. Also disclosed are methods of using such compounds in the treatment of conditions related to CYP17 enzyme, such as cancer, and pharmaceutical compositions comprising such compounds.