50903-49-6

Basic information

• Product Name: L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, pentafluorophenyl ester
• CAS NO: 50903-49-6
• Molecular Formula: C16H18F5NO4
• Molecular Weight: 383.315
• Mol File: 50903-49-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, pentafluorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, pentafluorophenyl ester(50903-49-6)
• EPA Substance Registry System: L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, pentafluorophenyl ester(50903-49-6)

Safety Data

• Hazardous Substances Data: 50903-49-6(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 13734-41-3 t-Boc-L-valine 
• 14533-84-7 pentafluorophenyl trifloroacetate 
• 96157-57-2 bis(pentafluorophenyl)sulfite 
• 13734-41-3 N-Boc-(S/R)-valine 

Downstream Products

• 504438-61-3 Boc-L-Val-L-pGlu-OBn 
• 504438-67-9 Boc-L-Val-L-Oxd-OBn 
• 540496-36-4 [(S)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyryl)-2-oxo-oxazolidin-4-yl]-acetic acid benzyl ester 
• 78058-06-7 Z-pGlu-Val-Pro-NH₂ 
• 182360-26-5 (S)-2-(1,1-Dimethyl-prop-2-ynylamino)-3-methyl-butyric acid pentafluorophenyl ester 
• 182360-28-7 L-N-(3,3-dimethyl-1-propenyl)valine pentafluorophenyl ester 
• 226067-32-9 C₄₉H₇₄Cl₃N₅O₁₄ 
• 226067-24-9 ((S)-1-{(2E,4E)-(1S,6S,7S)-1-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-7-methoxy-4,6-dimethyl-8-phenyl-octa-2,4-dienylcarbamoyl}-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 226067-11-4 ((S)-1-{(E)-(R)-1-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-iodo-allylcarbamoyl}-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 226067-07-8 (4E,6E)-(2S,3S,8S,9S)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid 
• 226067-34-1 {(S)-1-[(2E,4E)-(1S,6S,7S)-1-((S)-2-Hydroxy-1-methyl-ethyl)-7-methoxy-4,6-dimethyl-8-phenyl-octa-2,4-dienylcarbamoyl]-2-methyl-propyl}-carbamic acid tert-butyl ester 
• 226067-33-0 {1-[3-(tert-butyl-diphenyl-silanyloxy)-1-formyl-2-methyl-propylcarbamoyl]-2-methyl-propyl}-carbamic acid tert-butyl ester 
• 226067-39-6 C₄₇H₇₃N₅O₁₄ 
• 170872-85-2 dimethyl motuporine hydrate 

Relevant articles and documents

Antibacterial and antifungal activities of 2,3-pyrrolidinedione derivatives against oral pathogens

Among the novel approaches applied to antimicrobial drug development, natural product-inspired synthesis plays a major role, by providing biologically validated starting points. Tetramic acids, a class of natural products containing a 2,4-pyrrolidinedione

Stereoselective synthesis of pseudotripeptides incorporating uncommon bis-α-aminoacid derivatives and X-ray analysis. Part 3

Stereoselective synthesis of pseudotripeptides 4, 5, 6, 8, 9, 13 and 14, incorporating an uncommon bis(α-aminoacid) derivative, has been accomplished starting from the L-valine derived chiral synthon 1. The configuration of the introduced stereogenic cent

Total synthesis of (-)-muscoride A

The recently isolated cyanobacterium metabolite muscoride A was synthesized in 15 steps and in 4.3% overall yield. Novel structural features of this peptide antibiotic include the presence of a threonine-derived bioxazole core and an N-(1,1-dimethyl)allyl ('reverse prenyl') valine residue. In the context of our synthesis, efficient new strategies for the preparation of these segments were developed. The synthesis of two epimers of muscoride A allowed the unambiguous assignment of the relative and absolute configuration of the natural product by NMR and optical rotation analyses.