50906-95-1Relevant articles and documents
Asymmetric Synthesis of (+)-Nemorensic Acid - Revision of the Stereochemistry of the Pyrrolizidine Alkaloid Nemorensine
Dillon, Michael P.,Lee, Nadine C.,Stappenbeck, Frank,White, James D.
, p. 1645 - 1646 (1995)
(+)-Nemorensic acid, the necic acid constituent of the pyrrolizidine alkaloid nemorensine, is shown to be (2R,3R,5S)-2-carboxy-2,3,5-trimethyltetrahydrofuranacetic acid by synthesis from (R)-(+)-β-citronellol, and a corrected structure for the parent alkaloid nemorensine is established by a single crystal X-ray analysis.
OXYNEMORENSINE, AN ALKALOID FROM Senecio nemorensis L., VAR. subdecurrens GRISEB.
Klasek, Antonin,Sedmera, Petr,Vokoun, Jindrich,Boeva, Anna,Dvorackova, Svatava,Santavy, Frantisek
, p. 548 - 558 (2007/10/02)
From S. nemorensis L., var. subdecurrens GRISEB. there were isolated the previously obtained alkaloids nemorensine (I), retroisosenine (II), bulgarsenine (III) and, in addition, the alkaloid oxynemorensine which was assigned the structure VIII on the basis of the interpretation of the 1H-NMR, 13C-NMR, mass spectra, and on that of the identification of the products of hydrolysis and reduction.Furthemore, the isolation of the cis-nemorensic acid (V) as well as that of the unsaturated acid IV, and the transformation of bulgarsenine (III) to nemorensine (I) were described.