5091-02-1

Basic information

• Product Name: 1,2,5-triacetoxy-3,4-dimethyl-benzene
• Synonyms: 1,2,5-triacetoxy-3,4-dimethyl-benzene
• CAS NO: 5091-02-1
• Molecular Weight: 280.277
• Mol File: 5091-02-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2,5-triacetoxy-3,4-dimethyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-triacetoxy-3,4-dimethyl-benzene(5091-02-1)
• EPA Substance Registry System: 1,2,5-triacetoxy-3,4-dimethyl-benzene(5091-02-1)

Safety Data

• Hazardous Substances Data: 5091-02-1(Hazardous Substances Data)

Upstream product

• 526-86-3 2,3-dimethyl-1,4-benzoquinone 
• 108-24-7 acetic anhydride 

Downstream Products

• 1760-68-5 2-hydroxy-5,6-dimethylcyclohexa-2,5-diene-1,4-dione 
• 116664-63-2 1,2,5-triacetoxy-3,4-bis(bromomethyl)benzene 
• 2913-46-4 5-methoxy-2,3-dimethylcyclohexa-2,5-diene-1,4-dione 
• 4382-97-2 2-Hydroxy-5,6-dimethyl-hydrochinon 

Relevant articles and documents

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Diels-Alder Approaches to Model Compounds Related to Fredericamycin A

A series of model compounds related to the antitumor and antibiotic compound fredericamycin A has been prepared.Spiro-2,5-dione (2) has been prepared and established as a novel spiro dienophile in the Diels-Alder reaction with 1,3-butadiene, Danishefsky's diene, a triacetoxy-substituted o-quinodimethane, and two isobenzofuran intermediates.Thus, the cycloaddition of 3-cyano-4,5,7-trimethoxy-1(3H)-isobenzofuranone (35) and 2 afforded 4,9-dihydroxy-5,6,8-trimethoxyspiroindene-2,1'-indan>-1,3-dione (38) in 62percent yield.This methodology provides a viable synthetic route to the quinone portion of fredericamycin A that contains the seven requisite oxygens.