50912-92-0

Basic information

• Product Name: H-D-ARG(NO2)-OME HCL
• Synonyms: NG-NITRO-D-ARGININE-METHYL ESTER HCL;NG-NITRO-D-ARGININE METHYL ESTER HYDROCHLORIDE;N-OMEGA-NITRO-D-ARGININE METHYL ESTER HYDROCHLORIDE;nω-nitro-d-arginine methyl ester hydrochloride;NW-NITRO-D-ARGININEMETHYLESTERHYDROCHLORIDE;N5-Nitro-D-arginine methyl ester dihydrochloride;D-NAME, NG-Nitro-D-arginine methyl ester hydrochloride;NG-Nitro-D-arginine-methyl ester hydrochloride,99%
• CAS NO: 50912-92-0
• Molecular Formula: C₇H₁₅N₅O₄*ClH
• Molecular Weight: 269.69
• Product Categories: Amino Acids
• Mol File: 50912-92-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 150-160 °C
• Boiling Point: 410.7 °C at 760 mmHg
• Flash Point: 202.2 °C
• Appearance: Crystalline
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly, Sonicated), Water (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: H-D-ARG(NO2)-OME HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-ARG(NO2)-OME HCL(50912-92-0)
• EPA Substance Registry System: H-D-ARG(NO2)-OME HCL(50912-92-0)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 50912-92-0(Hazardous Substances Data)

Usage

Description

H-D-ARG(NO2)-OME HCL, also known as D-NG-Nitroarginine Methyl Ester Hydrochloride, is a crystalline inactive stereoisomer of L-NAME, which is a Nitric Oxide Synthase (NOS) inhibitor. It is derived from the chemical modification of the naturally occurring amino acid, L-arginine, and is characterized by its nitro group and ester functional groups. H-D-ARG(NO2)-OME HCL has been found to possess various biological activities and potential applications in different fields.

Uses

Used in Pharmaceutical Industry:
H-D-ARG(NO2)-OME HCL is used as a research compound for studying the role of nitric oxide (NO) in various physiological and pathological processes. As an inactive stereoisomer of L-NAME, it serves as a control in experiments involving the inhibition of NOS, which is an enzyme responsible for the production of nitric oxide.
Used in Agricultural Industry:
H-D-ARG(NO2)-OME HCL is used as a potential agent to reduce the necrotic and hypersensitive response of tobacco plants induced by Ralstonia solanacearum, a bacterium that causes brown rot in various crops. By inhibiting the NOS enzyme, this compound may help in mitigating the damage caused by the bacterial infection and improve the overall health of the plants.

Downstream Products

• 86807-84-3 Tos-Gly-Gly-N^G-nitro-L-Arg-OMe 
• 86807-78-5 Tos-L-Leu-N^G-nitro-L-Arg-NH₂ 
• 86807-77-4 Tos-L-Val-N^G-nitro-L-Arg-NH₂ 
• 86807-82-1 Tos-Gly-N^G-nitro-L-Arg-N₂H₃ 
• 86807-64-9 Tos-L-Leu-N^G-nitro-L-Arg-OMe 
• 86807-63-8 Tos-L-Val-N^G-nitro-L-Arg-OMe 
• 86807-65-0 Tos-Aba-N^G-nitro-L-Arg-OMe 
• 86807-88-7 Tos-Gly-Gly-Gly-N^G-nitro-L-Arg-OMe 
• 86807-66-1 Tos-3,4(OH)2Phe-N^G-nitro-L-Arg-OMe 
• 86807-62-7 Tos-Gly-N^G-nitro-L-Arg-OMe