510-65-6 Usage
Chemical structure
19-Hydroxy substances contain a hydroxyl group (OH) attached to the 19th carbon atom in their molecular structure.
Natural sources
These substances can be found in various natural sources, including plants and animals.
Laboratory synthesis
19-Hydroxy substances can also be synthesized in the laboratory.
Anti-inflammatory
They help reduce inflammation in the body.
Antioxidant
They protect cells from damage caused by free radicals.
Anticancer
They have the potential to inhibit or prevent the growth of cancer cells.
Hormone replacement therapy
They may help balance hormone levels in the body.
Treatment of hormone-related conditions
They could be used to manage conditions that are influenced by hormonal imbalances.
Ongoing research
19-Hydroxy substances continue to be the subject of ongoing research due to their potential therapeutic benefits for a variety of health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 510-65-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 510-65:
(5*5)+(4*1)+(3*0)+(2*6)+(1*5)=46
46 % 10 = 6
So 510-65-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H30O5/c1-19-7-5-17-15(16(19)6-9-21(19,26)18(25)11-22)3-2-13-10-14(24)4-8-20(13,17)12-23/h10,15-17,22-23,26H,2-9,11-12H2,1H3/t15-,16-,17-,19-,20+,21-/m0/s1
510-65-6Relevant articles and documents
A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids
Wang, Junlin,Zhang, Yanan,Liu, Huanhuan,Shang, Yong,Zhou, Linjun,Wei, Penglin,Yin, Wen-Bing,Deng, Zixin,Qu, Xudong,Zhou, Qianghui
, (2019/08/02)
Steroidal C19-hydroxylation is pivotal to the synthesis of naturally occurring bioactive C19-OH steroids and 19-norsteroidal pharmaceuticals. However, realizing this transformation is proved to be challenging through either chemical or biological synthesis. Herein, we report a highly efficient method to synthesize 19-OH-cortexolone in 80% efficiency at the multi-gram scale. The obtained C19-OH-cortexolone can be readily transformed to various synthetically useful intermediates including the industrially valuable 19-OH-androstenedione, which can serve as a basis for synthesis of C19-functionalized steroids as well as 19-nor steroidal drugs. Using this biocatalytic C19-hydroxylation method, the unified synthesis of six C19-hydroxylated pregnanes is achieved in just 4 to 9 steps. In addition, the structure of sclerosteroid B is revised on the basis of our synthesis.
