510-69-0

Basic information

• Product Name: [5R,13β,19R,(+)]-1,2-Didehydrocrinan-3β-ol
• Synonyms: [5R,13β,19R,(+)]-1,2-Didehydrocrinan-3β-ol;Vittatine;Crinan-3-ol, 1,2-didehydro-, (3beta,5alpha,13beta,19alpha)-;vittatine Trifluoroacetic acid
• CAS NO: 510-69-0
• Molecular Formula: C16H17NO3
• Molecular Weight: 271.31108
• Mol File: 510-69-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 456.3°C at 760 mmHg
• Flash Point: 229.8°C
• Appearance: /
• Density: 1.43g/cm³
• Vapor Pressure: 4.04E-09mmHg at 25°C
• Refractive Index: 1.707
• CAS DataBase Reference: [5R,13β,19R,(+)]-1,2-Didehydrocrinan-3β-ol(CAS DataBase Reference)
• NIST Chemistry Reference: [5R,13β,19R,(+)]-1,2-Didehydrocrinan-3β-ol(510-69-0)
• EPA Substance Registry System: [5R,13β,19R,(+)]-1,2-Didehydrocrinan-3β-ol(510-69-0)

Safety Data

• Hazardous Substances Data: 510-69-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H17NO3/c18-11-1-2-16-3-4-17(15(16)6-11)8-10-5-13-14(7-12(10)16)20-9-19-13/h1-2,5,7,11,15,18H,3-4,6,8-9H2/t11-,15+,16+/m1/s1

Upstream product

• 50-00-0 formaldehyd 
• 712281-00-0 (3aR,6S,7aS)-6-(tert-butyldimethylsilyloxy)-3a,6,7,7a-tetrahydro-3a-[3',4'-(methylenedioxy)phenyl]indoline 
• 17680-04-5 (3,4-methylenedioxy)phenylmagnesium bromide 
• 712280-92-7 (4S,6R)-4-benzyloxy-6-(tert-butyldimethylsilyloxy)-3-[3',4'-(methylenedioxy)phenyl]-2-cyclohexen-1-one 
• 712280-93-8 (1R,4S,6R)-4-benzyloxy-6-(tert-butyldimethylsilyloxy)-3-[3',4'-(methylenedioxy)phenyl]-2-cyclohexen-1-ol 
• 712280-99-4 tert-butyl (3aR,4S,6S,7aS)-3a-(benzo[1,3]dioxol-5-yl)-6-(tert-butyldimethylsilyloxy)-2,3,3a,6,7,7a-hexahydro-1H-indole-1-carboxylate 
• 712280-95-0 2-{(1'S,4'R,6'S)-1'-[3'',4''-(methylenedioxy)phenyl]-6'-benzyloxy-4'-(tert-butyldimethylsilyloxy)-2'-cyclohexenyl}ethanol 
• 712280-97-2 N-(tert-butoxycarbonyl)-N-{2-(1'S,4'R,6'S)-1'-[3,4-(methylenedioxy)phenyl]-4'-(tert-butyldimethylsilyloxy)-2'-cyclohexenyl}ethyl amine 
• 712280-94-9 {(1S,4R,6S)-1-[3',4'-(methylenedioxy)phenyl]-6-benzyloxy-4-(tert-butyldimethylsilyloxy)-2-cyclohexenyl}acetic acid ethyl ester 
• 712280-98-3 (3aR,4S,6S,7aS)-N-(tert-butoxycarbonyl)-6-(tert-butyldimethylsilyloxy)-3a,4,5,6,7,7a-hexahydro-4-hydroxy-3a-[3',4'-(methylenedioxy)phenyl]indoline 
• 945953-95-7 (3aR,4S,6S,7aS)-3a-Benzo[1,3]dioxol-5-yl-6-(tert-butyl-dimethyl-silanyloxy)-4-methylsulfanylthiocarboxyoxy-octahydro-indole-1-carboxylic acid tert-butyl ester 
• 712280-96-1 N-(tert-butoxycarbonyl)-N-{2-(1'S,4'R,6'S)-1'-[3,4-(methylenedioxy)phenyl]-6'-benzyloxy-4'-(tert-butyldimethylsilyloxy)-cyclohex-2'-enyl}ethyl-N-(p-toluenesulfonyl)-amine 
• 7700-86-9 (+/-)-oxo-crinine 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 

Downstream Products

• 510-67-8 (+/-)-crinine 
• 510-67-8 (+/-)-crinine 
• 510-67-8 epicrinine 
• 468-22-4 buphanisine 

Relevant articles and documents

Asymmetric synthesis method for crinum asiaticum alkaloid

The invention relates to an asymmetric synthesis method for crinum asiaticum alkaloid taking the asymmetric catalytic hydrogenation reaction as the key step. According to the method, through racemic asymmetric catalytic hydrogenation kinetic resolution for replacing cyclohexanone, quick asymmetric synthesis for 22 kinds of crinum asiaticum alkaloid comprising (-)-crinine, (+)-epivittatine, (+)-vittatine, (-)-epicrinine and the like and eight analogues is achieved concisely and efficiently.

Synthesis of biologically active natural products by [3?+?2] cycloaddition of non-stabilized azomethine ylides (AMY): Concepts and realizations

Non-stabilized azomethine ylides (AMY) which are represented as a zwitterionic form of a C[sbnd]N[sbnd]C unit having four electrons in three parallel atomic π orbitals perpendicular to the plane of the dipole, undergoes 1,3-dipolar cycloaddition to produc

A through intra-molecular to aromatization and efficient synthesis of the wenshu blue alkali and its analogue (by machine translation)

The present invention provides a through the intramolecular to aromatization and efficient synthesis of the wenshu blue alkali and analogues thereof, comprises the following 7 steps: aniline compound synthesis, synthesis of aniline compound, phenol compound synthesis, synthesis of cyclized product, two alcoholic compound synthesis, the synthesis of the compounds, grand crinum alkali and analogs thereof. The invention by transition metal-catalyzed coupling reaction in the molecule to aromatization similar biological pathways, while at the same time realize superior chemical and enantiomeric selectivity, this is biological synthesis the incomparable. This synthetic route step is short, and the product yield is high. (by machine translation)