51010-48-1Relevant articles and documents
Construction of C-C Bond via C-N and C-O Cleavage
He, Rong-De,Pang, Xiaobo,Shu, Xing-Zhong
, p. 635 - 640 (2020/04/07)
The construction of a C-C bond is a center subject in synthetic organic chemistry. The cross-electrophile coupling has provided a powerful tool to forge the C-C bond. However, this process generally requires organic halides, which has severely restricted
Benzylation of Arenes with Benzyl Halides under Promoter-Free and Additive-Free Conditions
Cheng, Xinqiang,Shan, Jiankai,Tian, Xinshe,Ren, Yun-Lai,Zhu, Yanyan
supporting information, p. 4404 - 4410 (2019/07/03)
It was found that benzyl chlorides and bromides could directly react with electron-rich arenes, which provided an example of promoter-free and additive-free benzylation of arenes. A variety of benzyl chlorides and bromides were treated with benzene rings to give the targeted products in low to high yields. The present conditions tolerated the vinyl group of the substrates. Preliminary mechanistic investigation suggests that the present reactions possibly proceed via an autocatalytic mechanism pathway.