51059-44-0 Usage
Uses
Wogonoside is a flavonoid present in extracts from plant Radic scutellariae and provides antioxidant activity.
Definition
ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of wogonin.
General Description
Natural product derived from plant source.
Biochem/physiol Actions
Wogonoside, a flavanoid, is known for its anti-inflammatory properties. Wogonoside may have therapeutic potential for use in diseases which involve the development of inflammation and angiogenesis through its inhibition of LPS-induced angiogenesis.
Check Digit Verification of cas no
The CAS Registry Mumber 51059-44-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,0,5 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51059-44:
(7*5)+(6*1)+(5*0)+(4*5)+(3*9)+(2*4)+(1*4)=100
100 % 10 = 0
So 51059-44-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1
51059-44-0Relevant articles and documents
Flavonoids from Roots of Scutellaria intermedia
Botirov, E. Kh.,Karimov
, p. 577 - 578 (2018/06/11)
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Purification and characterization of UDP-glucuronate: Baicalein 7-O- glucuronosyltransferase from Scutellaria baicalensis Georgi. cell suspension cultures
Nagashima, Shigeyuki,Hirotani, Masao,Yoshikawa, Takafumi
, p. 533 - 538 (2007/10/03)
UDP-glucuronate: baicalein 7-O-glucuronosyltransferase (UBGAT) catalyzes the transfer of glucuronic acid from UDP-glucuronic acid to the 7-OH of baicalein. UBGAT was purified from cultured cells of Scutellaria baicalensis Georgi (Lamiaceae). It was purified 95-fold using various chromatography and chromatofocusing procedures to apparent homogeneity. The M(r) was estimated to be 110 kDa by gel filtration chromatography with a 52 kDa subunit by SDS- PAGE. The isoelectric point was pH 4.8. UBGAT was specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe). (C) 2000 Elsevier Science Ltd.