510703-88-5

Basic information

• Product Name: 3-Pyridinamine,N-(2-furanylmethyl)-(9CI)
• Synonyms: 3-Pyridinamine,N-(2-furanylmethyl)-(9CI);Furan-2-ylmethyl-pyridin-3-yl-amine
• CAS NO: 510703-88-5
• Molecular Formula: C10H10N2O
• Molecular Weight: 174.1992
• Product Categories: AMINESECONDARY
• Mol File: 510703-88-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinamine,N-(2-furanylmethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinamine,N-(2-furanylmethyl)-(9CI)(510703-88-5)
• EPA Substance Registry System: 3-Pyridinamine,N-(2-furanylmethyl)-(9CI)(510703-88-5)

Safety Data

• Hazardous Substances Data: 510703-88-5(Hazardous Substances Data)

Upstream product

• 626-55-1 3-Bromopyridine 
• 617-89-0 furan-2-ylmethanamine 
• 1051946-59-8 3-(2-furoyl)amino-pyridine-2-phosphonic acid diethyl ester 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 462-08-8 pyridin-3-ylamine 
• 98-01-1 furfural 
• 626-60-8 3-Chloropyridine 
• 107658-27-5 pyridin-3-yl trifluoromethanesulfonate 

Relevant articles and documents

Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common Soluble Base in C-N Coupling

Due to the low intrinsic acidity of amines, palladium-catalyzed C-N cross-coupling has been plagued continuously by the necessity to employ strong, inorganic, or insoluble bases. To surmount the many practical obstacles associated with these reagents, we utilized a commercially available dialkyl triarylmonophosphine-supported palladium catalyst that facilitates a broad range of C-N coupling reactions in the presence of weak, soluble bases. The mild and general reaction conditions show extraordinary tolerance for even highly base-sensitive functional groups. Additionally, insightful heteronuclear NMR studies using 15N-labeled amine complexes provide evidence for the key acidifying effect of the cationic palladium center.

Aryne cycloaddition with 3-oxidopyridinium species

The [3 + 2] cycloaddition of arynes with 3-oxidopyridinium species is examined using the Kobayashi benzyne precursor. The reaction affords a bicyclo[3.2.1] skeleton under mild conditions. A [7 + 2] cycloaddition mode with a subsequent pyridine ring-opening event has also been observed.

Mild and efficient copper-catalyzed amination of aryl bromides with primary alkylamines

(Matrix presented) An efficient copper-catalyzed amination of aryl bromides with primary alkylamines was developed that uses commercially available diethylsalicylamide as the ligand. This amination reaction can be performed at 90°C in good yield. A variety of functional groups are compatible with these reaction conditions. Preliminary results show that this reaction can be carried out under solvent-free conditions with comparable yields.