511-82-0Relevant articles and documents
Djerassi et al.
, p. 3783,3786 (1956)
Biotransformation of oleanolic and maslinic acids by Rhizomucor miehei
Martinez, Antonio,Rivas, Francisco,Perojil, Alberto,Parra, Andres,Garcia-Granados, Andres,Fernandez-Vivas, Antonia
, p. 229 - 237 (2013/10/22)
Microbial transformation of oleanolic acid by Rhizomucor miehei produced three metabolites. A known compound, a 30-hydroxyl derivative (queretaroic acid), and two 7β,30- and 1β,30-dihydroxylated metabolites, respectively. The action of the same fungus (R. miehei) on maslinic acid produced an olean-11-en-28,13β-olide derivative, a metabolite hydroxylated at C-30, an 11-oxo derivative, and two metabolites with an 11α,12β- epoxy group, hydroxylated or not at C-30. Their structures were elucidated by extensive analyses of their spectroscopic data, and also by chemical correlations.