5110-45-2

Basic information

• Product Name: N-(diphenylethenylidene)-4-methylaniline
• Synonyms: Benzenamine, N- (diphenylethenylidene)-4-methyl-; N-p-Tolyl-2,2-diphenylvinylideneamine
• CAS NO: 5110-45-2
• Molecular Formula: C₂₁H₁₇N
• Molecular Weight: 283.3664
• Mol File: 5110-45-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 455.9°C at 760 mmHg
• Flash Point: 222.3°C
• Density: 0.98g/cm³
• Vapor Pressure: 4.59E-08mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: N-(diphenylethenylidene)-4-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(diphenylethenylidene)-4-methylaniline(5110-45-2)
• EPA Substance Registry System: N-(diphenylethenylidene)-4-methylaniline(5110-45-2)

Safety Data

• Hazardous Substances Data: 5110-45-2(Hazardous Substances Data)

Upstream product

• 5110-46-3 2-chloro-2,2-diphenyl-N-p-tolyl-acetimidoyl chloride 
• 102311-01-3 2,2-diphenyl-N-p-tolyl-acetimidoyl chloride 
• 4107-01-1 N-(p-tolyl)diphenylacetamide 
• 76711-20-1 chlore-methylene-di(tert-butyle)phosphorane 
• 28195-19-9 diphenylthioacetato-4-toluide 
• 32177-09-6 chloro-diphenyl-acetic acid p-toluidide 
• 1871-76-7 diphenylacetic acid chloride 
• 2327-67-5 N-(p-tolyl)-P,P,P-triphenylphosphine imide 
• 117-34-0 2,2-diphenylacetic acid 

Downstream Products

• 112745-35-4 2,2-diphenyl-N-p-tolyl-acetimidic acid methyl ester 
• 7474-32-0 2,2-diphenyl-N-p-tolyl-acetimidic acid ethyl ester 
• 7472-92-6 N-diphenylacetyl-N-(2,4,6-trimethyl-benzoyl)-p-toluidine 
• 7472-87-9 N,N-bis-diphenylacetyl-p-toluidine 
• 103210-96-4 1,1,2-triphenyl-2-p-tolylimino-ethyl hydroperoxide 
• 4107-01-1 N-(p-tolyl)diphenylacetamide 
• 102311-01-3 2,2-diphenyl-N-p-tolyl-acetimidoyl chloride 
• 102474-67-9 1,1-diphenyl-2-p-toluidino-ethanol 
• 7463-06-1 N,N-phthaloyl-β-alanine-(N-diphenylacetyl-p-toluidide) 
• 7494-88-4 N,N-phthaloyl-glycine-(N-diphenylacetyl-p-toluidide) 
• 95460-01-8 N-Acetyldiphenylacetotoluidide 
• 7465-75-0 N-(N-benzyloxycarbonyl-glycyl)-N-diphenylacetyl-p-toluidine 
• 103280-62-2 N-benzoyl-N-diphenylacetyl-p-toluidine 
• 120831-43-8 N,N-phthaloyl-methionine-(N-diphenylacetyl-p-toluidide) 

Relevant articles and documents

Base-mediated regioselective [3+2] annulation of ketenimines and isocyanides: Efficient synthesis of 1,4,5-trisubstituted imidazoles

A novel base-mediated regioselective [3+2] annulation of active methylene isocyanides with ketenimines has been developed. In the presence of t-BuOK, a wide range of ketenimines readily react with active methylene isocyanides in DMF at 40 °C to afford 1,4

Preparation of 1,2,5-Trisubstituted 1H-Imidazoles from Ketenimines and Propargylic Amines by Silver-Catalyzed or Iodine-Promoted Electrophilic Cyclization Reaction of Alkynes

From readily available propargylic amines, 1,2,5-trisubstituted imidazoles are efficiently obtained through a cascade reaction catalyzed by AgOTf or promoted by molecular iodine. The AgOTf-catalyzed reaction involves nucleophilic addition of propargylic amine to ketenimine, a silver-catalyzed electrophilic cyclization reaction of alkyne, and a tautomerism/isomerism/metal-H exchange cascade. The iodine-mediated counterpart yields 5-formyl-1,2-disubtituted imidazoles, which presumably includes a cascade hydrolysis/oxidation reaction. Furthermore, the presented protocol can be scaled up and the resultant 1,2,5-trisubstituted imidazole can be converted into fused indeno[1,2-d]imidazole. 1,2,5-Trisubstituted imidazoles are efficiently prepared from readily available propargylic amines through a AgOTf-catalyzed or molecular iodine-promoted cascade reaction. The presented protocol can be scaled up and the resultant 1,2,5-trisubstituted imidazoles can be converted into fused indeno[1,2-d]imidazoles.

Ketenimine Chemistry. Part 1. The Reaction of Triaryl Ketenimines with Arenesulphenyl Chlorides

Benzenesulphenyl chloride reacts with diphenyl-N-p-tolylketenimine in diethyl ether solution to give N-(1-chloro-2,2-diphenyl-2-phenylthioethylidene)-p-toluidine (IV), via the attack of electrophilic sulphur on the terminal carbon of the ketenimine.